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Understanding the Digestive Tract and Accessory Glands

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The Digestive System

The digestive system transforms food into nutrients that are the right size to reach body cells and be absorbed. To carry out this function, the digestive system consists of a group of organs and structures: the digestive tract and the accessory glands.

The Digestive Tract

The digestive tract, in order from top to bottom, includes:

  • Mouth: The entry point of the digestive tract. It contains:
    • Teeth to bite and break food into small pieces.
    • A tongue to mix and swallow food, and enable the sense of taste.
    • Salivary glands.
  • Pharynx: A cavity shared by the digestive and respiratory systems. Food passes towards the esophagus. The epiglottis, a small, flexible cartilage, prevents food from reaching the respiratory tract.
  • Esophagus: A tube
... Continue reading "Understanding the Digestive Tract and Accessory Glands" »

VSG and Winterbottom's Sign in Trypanosoma Pathogenesis

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What is VSG and why is it important in pathogenesis caused by Trypanosoma?

VSG stands for Variant Surface Glycoprotein, and it plays a crucial role in the pathogenesis caused by Trypanosoma, the parasitic protozoa responsible for diseases like African trypanosomiasis.

The importance of VSG lies in its ability to undergo antigenic variation. Trypanosomes have a dense coat of VSG on their cell surface, providing a protective barrier against the host's immune system. The parasite, however, can continually switch between different VSG variants, making it challenging for the host's immune system to mount an effective and lasting defense.

This antigenic variation is a key survival strategy for Trypanosoma during the course of infection. As the immune... Continue reading "VSG and Winterbottom's Sign in Trypanosoma Pathogenesis" »

The Endocrine System: Glands, Hormones, and Their Vital Functions

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The Endocrine System

The endocrine system is comprised of glands that produce protein substances called hormones. These hormones act as chemical messengers, speeding up or slowing down various activities within the body's cells.

Types of Glands

Exocrine Glands

Exocrine glands release substances through ducts to specific locations. These substances include enzymes, oil, and sweat. Examples include:

  • Salivary glands
  • Sweat glands
  • Oil glands
  • Gastric glands
  • Intestinal glands

Endocrine Glands

Endocrine glands produce and secrete hormones directly into the bloodstream, acting on target cells throughout the body. Examples include:

  • Pituitary gland
  • Thyroid gland
  • Adrenal glands
  • Ovaries
  • Testes

Hormones: Action and Functions

Hormones act on specific target cells by binding... Continue reading "The Endocrine System: Glands, Hormones, and Their Vital Functions" »

Evolution and Genetics: A Comprehensive Guide

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Gene Pool

The gene pool is the sum of all genetic information carried by all the individuals of a population.

Mutations

Mutations are the ultimate source of all genetic variation, and are the result of random changes in DNA sequences.

Gene Flow

Gene flow is the movement of genes from one population to another. It occurs when individuals migrate from one population to another, thus bringing their genes with them.

Genetic Drift

Genetic drift is a random process where certain alleles are removed from the population by accidental events. It is more likely to affect small populations than larger ones.

Founder Effect

The Founder Effect occurs when a small group of individuals establishes a new population far from existing populations. Because this group is... Continue reading "Evolution and Genetics: A Comprehensive Guide" »

Oral Lesions, Blood Disorders, and Related Conditions

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Oral Diseases Associated with HIV

Group 3: Lesions Associated with HIV

  • Bacterial infections (e.g., Actinomyces israelii, Escherichia coli pneumonia)
  • Cat-scratch disease
  • Drug reactions (ulcerative, toxic epidermal necrolysis)
  • Fungal infections (e.g., Cryptococcus neoformans, Geotrichum candidum)
  • Neurological disturbances (e.g., facial palsy, trigeminal neuralgia)
  • Viral infections (e.g., cytomegalovirus)

Kaposi's Sarcoma

Multifocal, vascular neoplasm.

  • Decreased immunocompetence activates the latent virus.
  • Palate and gingiva are the most common sites.
  • Painless red macules progress to nodular lesions.

Differential Diagnosis

  • Hemangioma
  • Varicosity
  • Bacillary angiomatosis
  • Pyogenic granuloma

Treatment

  • Intralesional injections of vinblastine 0.1 mg/cm2 or 0.2 mg/mL saline.
... Continue reading "Oral Lesions, Blood Disorders, and Related Conditions" »

The Formation and Development of a New Individual

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After ovulation, the ovum may be fertilized.

Embryonic Development

Embryonic development lasts approximately nine months, from fertilization to implantation.

Fertilization

Fertilization is the process in which a spermatozoon and an ovum join together to create a zygote in the Fallopian tubes.

Cleavage

The first divisions of the zygote, known as cleavage, occur while it travels down to the uterus. This process turns it from a zygote into an embryo.

Implantation

When the embryo arrives in the uterus, it embeds in the endometrium.

The Formation of the Placenta and the Amniotic Sac

Once the embryo is implanted, two structures are formed to protect it and provide it with nourishment. The placenta is an organ which links the embryo to its mother through the
... Continue reading "The Formation and Development of a New Individual" »

Understanding Natural Selection and Its Role in Evolution

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Natural Selection:

Variation is the slight individual differences within populations.

Some variations are inherited (passed on from parents) and some are acquired (developed during life). Only inherited variation is passed on to the next generation.
Animals and plants produced by sexual reproduction will show variation from their parents, for example, in the size of the muscles in the legs of lions.
When new organisms are produced, not all of them are likely to survive because of competition for resources such as food, water, and shelter. The same is true for plants (they compete for resources such as nutrients, light, water, and space).
The individuals with the most favorable characteristics are most likely to survive.

The process of natural selection... Continue reading "Understanding Natural Selection and Its Role in Evolution" »

Human performance

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HEALTH-Physical mental and social well being

What is a disease?

Change in the body that produces a loss of health. Common terms:

Aetiology Symptom and Sign

Classification of siseases

By the organ or system affected. By persistence: acute or chronic or by transmissibility: infectious or non infectious

-infectious diseases. Caused by pathogens

-Non infectious diseases. Not caused by pathogens

TRANSMISSION OF INFECTIOUS DISEASES

Agent - pathogen that causes a disease

Reservoir. The place where pathogen lives

Vector. The person animal or microorganism that carries and transmits the agent or pathogen

Host. The organism that is infected

Transmission of pathogens

-Direct contact

-Indirect contact

Portals of entry into host

Skin, Respiratory tract, Digestive tract

... Continue reading "Human performance " »

Characteristics of Fungi, Protozoa, Algae, and Monera Kingdoms

Classified in Biology

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FUNGI KINGDOM

Cellular Organization:

Unicellular or multicellular, the cells are eukaryotic, they have no tissues.

Size and Shape:

Unicellular fungi, like yeast, are round or oval and microscopic in size.

Nutrition:

Heterotrophic, many are saprophytes, feeding on organic material from animals or plants.

Lifestyle:

They can be free-living symbionts or parasites.

Reproduction:

Unicellular asexual, multicellular asexual, or sexual.

PROTOCTIST KINGDOM PROTOZOA

Cellular Organization:

Unicellular, they have no tissues.

Size and Shape:

Oval, round, oblong, half-moon. All are microscopic.

Nutrition:

Heterotrophic, feeding on bacteria and algae.

Habitat and Lifestyle:

Most are free-living.

Reproduction:

They reproduce asexually by binary fission.

Movement:

They move by using... Continue reading "Characteristics of Fungi, Protozoa, Algae, and Monera Kingdoms" »

Understanding Emotions and Hormones in Relationships

Classified in Biology

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Embarrassment:

When something is sudden and unexpected, onlookers are amused. It is a social mistake and makes the person the center of attention. Feeling empathetic for someone else's embarrassment is a display of care. People are often forgiven for their mistakes because they blush, which makes them feel smaller. Embarrassment peaks during teenage years (pregenual ant. cingulate cortex).

Shame:

Shame occurs when a person has failed to live up to expectations or has done something morally wrong. Onlookers are angry, and it often involves poor performance or hurting someone's feelings by failing to meet their expectations.

Guilt:

Guilt is the result of failing to perform one's duty, such as lying, cheating, or stealing (Medial prefrontal, visual... Continue reading "Understanding Emotions and Hormones in Relationships" »