Physical Pharmacy: Rheology, Colloids, and Flow Properties
Peptization
The process of converting a precipitate into a colloidal solution by shaking with a suitable electrolyte is called peptization. The electrolyte acts as a stabilizing agent, known as a peptizing agent.
Kinematic Viscosity
Defined as the ratio of viscosity to the density of a fluid. It is denoted by ν (nu), where ν = η/ρ.
Porosity
The ratio of void volume to bulk volume. It is denoted by ε.
Law of Flow
Shear stress is directly proportional to the rate of shear strain (τ ∝ dv/dr).
Newtonian and Non-Newtonian Fluids
- Newtonian Fluid: Obeys Newton's law of flow; viscosity remains constant. Examples: H₂O, glycerine, oil, glasses.
- Non-Newtonian Fluid: Does not obey Newton's law of flow; exhibits variable viscosity. Examples: Butter, gum,
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