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Cell Biology and Genetics: Core Definitions and Principles

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Essential Concepts in Biology and Heredity

Fundamental Definitions in Genetics

Gene

The basic unit of heredity passed from parent to child. Genes are made up of sequences of DNA and are arranged, one after another, at specific locations on chromosomes in the nucleus of cells.

Codominance

Codominance, as it relates to genetics, refers to a type of inheritance in which two versions (alleles) of the same gene are expressed separately to yield different traits in an individual.

Cellular Components and Principles

Ribosomes

Small particles with two subunits, without membranes to divide them. They are responsible for building proteins using the information coded in a linear molecule of nucleic acid (RNA).

Mendel's Second Law of Segregation

Mendel's second law... Continue reading "Cell Biology and Genetics: Core Definitions and Principles" »

Human Body Systems: Digestion, Respiration, and Excretion

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The Human Digestive System: Function and Components

The digestive system transforms food into nutrients, which are then transported by the circulatory system through the blood to the cells. It is a set of organs and structures, including the digestive tract and accessory glands.

Key Components of the Digestive System

  • Mouth
  • Pharynx
  • Oesophagus
  • Stomach
  • Small Intestine
  • Large Intestine
  • Appendix
  • Salivary Glands
  • Liver
  • Pancreas

Initial Digestion: Mechanical and Chemical Processes

Digestion is the transformation of food into nutrients so that cells can benefit from them. It can be mechanical or chemical. Digestion begins in the mouth immediately after food is ingested.

Processes and Elements in Oral Digestion

  • Mastication (Chewing)
  • Food
  • Tongue
  • Salivary Glands
  • Bolus formation
... Continue reading "Human Body Systems: Digestion, Respiration, and Excretion" »

Origin of Life and Evolution: Theories and Evidence

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Theories on the Origin of Life

The primordial soup hypothesis is incapable of explaining the origin of life because the early atmosphere wasn't composed of the gases described by Oparin and Haldane. Also, we know that in the early atmosphere, there was no ozone layer, so it would make the first molecules very unstable because of UV radiation. The hypothesis was supported by the Miller-Urey experiment, which consisted of the following: a mixture of gases was put in a container, and high-voltage electric shocks were applied. Then, gases were condensed in another container, simulating the primitive ocean. Finally, several organic compounds were found in that simulated "primordial soup," including amino acids. As an alternative to the primordial... Continue reading "Origin of Life and Evolution: Theories and Evidence" »

Cellular Respiration: Aerobic vs. Anaerobic Processes

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Respiration: The Energy Source of Life

Every living cell needs energy. In humans, our cells need energy for:

  • Contracting muscles
  • Making proteins
  • Making new cells
  • Cell division
  • Producing heat inside the body

All of this energy comes from the food that we eat. The food is digested (broken down) and absorbed from the intestine into the blood. Then, the blood goes to the body, and the cells take the nutrients.

Aerobic Respiration

Most of the time, our cells release energy from glucose by combining it with oxygen.

Aerobic respiration involves chemical reactions in cells that use oxygen to break down nutrient molecules to release energy.

glucose + oxygen → carbon dioxide + water

Anaerobic Respiration

Anaerobic respiration involves chemical reactions in cells... Continue reading "Cellular Respiration: Aerobic vs. Anaerobic Processes" »

Exploring the Microscopic World: Cells, Organelles, and Cellular Processes

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Chapter 1: Introduction to Cells and Microscopy

1.1 What are Living Things?

Organism: A living thing made up of cells.

Cell: The smallest living part of a living thing.

Unicellular: Single-celled organisms.

Multicellular: Organisms made of many cells.

Characteristics of All Living Things:

  • Responds to its environment
  • Needs energy
  • Grows
  • Reproduces
  • Gets rid of wastes that build up in its body

Exploring the Microscopic World:

Compound Microscope: Combines two lenses to magnify objects.

Light Microscope: Uses light to view an object.

Resolving Power: The ability of a microscope to focus on two objects or details that are close together.

Magnification Power: The ability of a microscope to make an object appear larger.

Eyepiece: The lens you look through to magnify... Continue reading "Exploring the Microscopic World: Cells, Organelles, and Cellular Processes" »

Human Reproduction: Life Stages & Systems

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Human Reproduction & Sexuality

Human reproduction is sexual and has two key characteristics:

  • The new individual is formed from a single cell called a zygote.
  • Zygotes result from the union of two gametes (fertilization).

Humans have two types of gametes: sperm (men) and ova (women).

Changes During Reproductive Life

During the reproductive life of a human being, there are three main stages:

  • Puberty

    Puberty begins in men with the first ejaculation (spermarche) and in women with the first menstruation (menarche). This is due to the increased secretion of pituitary hormones: Follicle-Stimulating Hormone (FSH) and Luteinizing Hormone (LH), which stimulate gamete production.

    Puberty typically begins when girls are 10-13 years old and boys 12-14. It lasts

... Continue reading "Human Reproduction: Life Stages & Systems" »

Photosynthesis vs. Cellular Respiration: Energy Production

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Fundamental Biological Energy Processes

Photosynthesis and Cellular Respiration: Key Equations

  • Photosynthesis: Converts light energy into chemical energy (glucose).

    6CO₂ + 6H₂O → C₆H₁₂O₆ + 6O₂

  • Cellular Respiration: Breaks down glucose to release energy (ATP).

    C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O

Purpose and Scope of Energy Conversion

Photosynthesis allows plants and algae to make their food by converting light energy from the sun into chemical energy stored in glucose.

Cellular Respiration is the process used to generate usable energy, primarily in the form of Adenosine Triphosphate (ATP). ATP is the energy currency of the cell, essential for carrying out all cellular functions.

Organisms Performing These Processes

  • Photosynthesis
... Continue reading "Photosynthesis vs. Cellular Respiration: Energy Production" »

Understanding DNA Mutations and Chromosomal Anomalies

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DNA Mutations

Mutations are alterations to a DNA sequence that occur when a gene is damaged or changed, altering the genetic message. These mutations can have varying effects on health, depending on their location and whether they alter essential protein functions.

Mutations can occur at three levels:

  1. Molecular (Gene or Point)
    • These mutations affect the chemical constitution of genes, specifically the DNA bases.
  2. Chromosomal
    • These mutations affect a segment of a chromosome, altering its structure through deletions, duplications, or rearrangements.
  3. Genomic
    • These mutations affect the entire genome, altering the number of chromosome sets (polyploidy or haploidy) or individual chromosomes (e.g., trisomy 21).

Mutations can be of different types:

  1. Gene Mutations:
... Continue reading "Understanding DNA Mutations and Chromosomal Anomalies" »

Digestive System Processes: A Comprehensive Guide

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Digestive Phases

Cephalic Phase

The cephalic phase initiates digestion before food even reaches the stomach. Sensory cues like taste, smell, or even the thought of food trigger the central nervous system to stimulate gastric juice production.

Gastric Phase

Once food enters the stomach, receptors signal the brain, which in turn promotes further gastric juice secretion to break down the ingested food.

Intestinal Phase

As food moves into the duodenum, receptors detect its presence and signal the brain to increase the production of digestive juices for further processing.

Enterogastric Reflex

When the duodenum is full, the enterogastric reflex is activated, causing the pyloric sphincter to close and regulate the passage of chyme from the stomach to the... Continue reading "Digestive System Processes: A Comprehensive Guide" »

Dental Anatomy of Lower Premolars and Mandibular Growth

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Lower First Premolar

Prominent Elevations & Depressions/Snake-Snail Eye Lingually

Chronology

  • Enamel: 5-6 years old
  • Eruption: 10-11 years old
  • Root: 12-13 years old

Geometry

  • Lingual/Buccal: Trapezoid; short side cervical
  • Mesio-Distal: Rhomboidal
  • Occlusal: Diamond

Buccally

  • Cervical Ridge
  • Buccal Ridge
  • Mesio-Distal Buccal Developmental Groove

Lingually

  • Mesio-lingual Developmental Groove

Mesially

  • Mesio-lingual Developmental Groove

Mesial Contact Area

  • Junction between buccal and middle thirds

Distal Contact Area

  • Middle third

Occlusally

  • 2 well-developed cusps
  • Each cusp: triangular ridge
  • Mesial/Distal Marginal Ridges
  • Triangular Fossae
  • Developmental Pits
  • Central Developmental Groove
  • Transverse Ridge
  • Mesio-lingual Developmental Groove

Lower Second Premolar

3-Cusp Type has 5 Lobes

... Continue reading "Dental Anatomy of Lower Premolars and Mandibular Growth" »