Clinical Applications and Resistance of Antibiotics in Oral Surgery
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Combination of Antibiotics
Used when there is a mixed infection, or for the following reasons:
- Where the infectious organism is not known.
- Where the two antibiotics can produce a greater effect (synergism) than one alone.
- To prevent the development of resistance to one antibiotic.
Indications for Antibiotics
Curative Treatment
The primary aim when:
- Infection cannot be treated with surgery.
- As supplements to surgery (adjunctive therapy).
- In cases of osteomyelitis and actinomycosis.
Prophylactic Treatment
Starting approximately one hour before surgery.
Absolute Indications
- Prevention of subacute bacterial endocarditis before surgical procedures.
- Diabetic patients undergoing major oral surgery.
- Immunocompromised patients.
- Oral surgery in patients previously subjected