Brachytherapy Protocols for Oncology: Clinical Standards
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Eye Tumors
For tumors >15 mm or thickness >10 mm, enucleation is indicated. Otherwise, episcleral plaque brachytherapy is used.
- Isotopes: I-125 (<6 mm).
- Required Data: Tumor drawing, eye diameter, basal diameter, and maximum/minimum tumor thickness. Data is transferred to specific planning software (seeds, activity, position, duration).
- Treatment: Surgical application of episcleral plaques under anesthesia, covering the tumor base with a 2-3 mm margin.
- I-125: Dose 85 Gy (melanoma) and 40 Gy (retinoblastoma); dose rate 0.6-1.05 Gy/h.
- RU-106: Dose 100-130 Gy; dose rate 7.2-12 Gy/h. Inpatient care required.
Breast Tumors
Indications include tumor bed boost, accelerated partial breast irradiation, and HDR for local recurrence.
- Boost Requirements: