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Cancer Burden, Prevention, Treatment and Social Impact

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Social and Medical Problems of Malignant Tumors

14. Social and medical problems of malignant tumors. The potential of prevention

Background

Incidence – 500/100,000

Increases > 70 years

  • Mortality – 260/100,000
  • 216 thousand hospitalizations
  • Very serious and generally one of the most feared diseases

Most Frequent Tumours

  • Men: Bronchi/Lung - Colorectal - Prostate - Kidney - Stomach
  • Women: Breast - Cervical/Uterine - Colorectal - Bronchi/Lung - Kidney
  • Multiple Primary Tumors – occurrence of more than one primary tumor at different sites in the body

(1/10 malignant tumors)

Mortality Rates: see table

Treatment

  • Oncology departments
  • New therapeutic methods
  • Irradiation
  • Chemotherapy
  • Biological treatments
  • Note:

The most frequent treatment: chemotherapy (41.4%) and

... Continue reading "Cancer Burden, Prevention, Treatment and Social Impact" »

Kitchen Essentials and Classroom Event Ideas

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Essential Kitchen Tools

Here are some common kitchen tools and their uses:

  • Peeler: Used to peel carrots, potatoes, etc. (to remove the skin of vegetables).
  • Ice Tray: Water is put into the container and placed in the freezer so that ice cubes are formed.
  • Spatula: Used to handle food. For example, if you are cooking a hamburger, you can turn it or remove it with a spatula.
  • Strainer: Used, for example, when you make macaroni. Put the pasta in the strainer to drain the water, leaving the pasta behind.
  • Cutting Board: Used as a support when cutting food, preventing knife marks on the counter or other kitchen surfaces.

More Kitchen Items

  • Wok / Frying Pan (sartén)
  • Strainer (colador)
  • Saucepan (cacerola)
  • Peeler (pelador)
  • Rolling Pin (rodillo)
  • Casserole Dish (molde)
... Continue reading "Kitchen Essentials and Classroom Event Ideas" »

Thematic English-Spanish Vocabulary Lists

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English-Spanish Vocabulary Lists by Topic

Personality Traits

  • Ambitious (ambicioso) vs. Pushy (sin escrúpulos)
  • Assertive (asertivo) vs. Bossy (mandón)
  • Broad-minded (de mente abierta) vs. Narrow-minded (de mente cerrada)
  • Determined (decidido) vs. Stubborn (cabezón)
  • Easy-going (fácil de tratar) vs. Nervous (nervioso)
  • Generous (generoso) vs. Tight-fisted (tacaño)
  • Frank (franco) vs. Brusque (brusco)
  • Gifted (talentoso) vs. Slow (lento)
  • Mature (maduro) vs. Immature (inmaduro)
  • Modest (modesto) vs. Big-headed (creído)
  • Tactful (con tacto) vs. Tactless (sin tacto)
  • Outgoing (sociable) vs. Reserved (reservado)
  • Self-confident (seguro de sí mismo) vs. Arrogant (arrogante) or Insecure (inseguro)

Buying and Selling

  • Afford (permitirse algo)
  • Bargain (ganga)
  • Cash (dinero
... Continue reading "Thematic English-Spanish Vocabulary Lists" »

Epinephrine Synthesis, Adrenergic Receptors & Pharmacology

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Epinephrine and Norepinephrine Synthesis

The synthesis pathway for catecholamines like norepinephrine and epinephrine is as follows:

  1. Phenylalanine is converted to Tyrosine.
  2. Tyrosine is taken into the neuron via a transporter.
  3. Tyrosine is converted to L-DOPA by the enzyme Tyrosine Hydroxylase. (This is the rate-limiting step in the pathway).
  4. L-DOPA is converted to Dopamine by the enzyme Dopa Decarboxylase.
  5. Dopamine is transported into a vesicle via the Vesicular Monoamine Transporter (VMAT).
  6. Inside the vesicle, Dopamine is converted to Norepinephrine by the enzyme Dopamine Beta-Hydroxylase.
  7. Synthesis may stop at Norepinephrine, depending on the cell type.
  8. In the adrenal medulla, Norepinephrine can be further converted to Epinephrine by the enzyme Phenylethanolamine
... Continue reading "Epinephrine Synthesis, Adrenergic Receptors & Pharmacology" »

Transforming Stress into a Positive Force

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Can Stress Be Helpful for Us?

We know what stress is and how it can affect people, but can stress be helpful for us? Can we make stress our friend? How?

(Video: How to make stress your friend)

Stress is a physical and mental condition that occurs when we adapt to the environment. There are some events that produce this internal state, such as work pressure, marital problems, financial problems, travel, dating, or getting a new job. Stress can be a major behavioral risk if it’s severe or prolonged, but it is not always bad. In this way, we know what stress is and how it can affect people, but can stress be helpful for us?

The Impact of Long-Term Stress

On the one hand, long-term stress produces maladaptive changes. Its impact can be understood... Continue reading "Transforming Stress into a Positive Force" »

Unusual Events and Everyday Situations: Anecdotes

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A Widow's Request at the Funeral Home

A widow took a look at her dear departed…

  1. He died because he was struck by lightning.
  2. The woman was angry because they had put him in the brown suit, and she wanted him in the blue suit.
  3. Because the woman said she was the one who paid.
  4. He did not change the suit. He changed the body and put the head on another body.
  5. a) To change. b) Changing.
  6. If the widow had not insisted, they would not have changed the suit.
  7. Dead - Departed. Start - Begin. Quick - Speedy. Exchange - Switch.
  8. a) Brought b) Said.

English Lessons on the Train

When I saw English lessons only written...

  1. He was invited to attend a class and see how it worked. He had to travel 40 miles to Eidsvoll and get up at six in the morning.
  2. He was initiated by the
... Continue reading "Unusual Events and Everyday Situations: Anecdotes" »

Otolaryngology Review

Classified in Medicine & Health

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Guideline

1. Focus on Solving (All / None)

2. Focus on Solving (T/F)

3. Focus on Solving Subject by Subject

Moderate Allergy Tx

(C)

Aphyxia

->(ER Tracheostomy)

Larynx Abd

->(C-A-P)

Allergy

-> Pale mucosa!

Septal Resection Does Not Cause

-> Nasal Polyp

Photoan

-> Weak VC

Contact Ulcer

-> Vocal abuse!

VC Lateral

-> Paralysis

VC Constriction

-> Functional aphonia!

Bullous Myringitis

-> PS Aeruginosa!

Normal Skin

-> Except diphtheria!

Swelling of Inner Orbital

-> ALL

Sinuses

  • Posterior Ethmoid -> (Superior meatus)
  • Max sinus -> Middle meatus
  • Max sinus -> at nose level

Tonsillitis

  • Acute (NOT) Nasopharyngeal obstruction
  • Chronic (Not) -> bad smell!
  • Hypertrophy (compli) -> Otitis media + Hearing loss
  • Chronic (except) -> systemic features!
... Continue reading "Otolaryngology Review" »

Thermal Emergencies: Causes, Diagnosis, and Management

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Hyperthermia: Causes, Diagnosis, and Treatment

Causes of Hyperthermia

The body's normal temperature is controlled by the Hypothalamus, which maintains thermal homeostasis. Hyperthermia occurs when the thermoregulatory mechanism is overwhelmed by:

  1. Increased environmental heat or strenuous exercise.
  2. Increased heat production by the body (e.g., metabolic disorders).
  3. Decreased heat emission or impaired thermoregulation.

Diagnosis (Dx) of Hyperthermia

I. Clinical Features (CF)

  • Sweating (may be absent in severe heatstroke)
  • Central Nervous System (CNS) changes (e.g., confusion, delirium)
  • Tachycardia
  • Pupillary changes

II. Instrumental and Laboratory Tests

  • Body Temperature Measurement (Core temperature is essential)
  • ECG: May show QRS widening or Osborn waves.
  • Blood
... Continue reading "Thermal Emergencies: Causes, Diagnosis, and Management" »

Secondary Hypertension and Bariatric Surgery

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Secondary Hypertension

Causes of Secondary Hypertension

  • Renal: Stenosis, PCKD, Obstruction
  • Endocrine: Cushing's syndrome, Adrenogenital syndrome, Pheochromocytoma, Acromegaly
  • Aorta Coarctation
  • Other: Thyroid disorders, Hypercalcemia

Red Flags in Secondary Hypertension

  • Hypokalemia
  • Early age of onset
  • Patient over 50 years old
  • High severity
  • Refractory to therapy
  • Increased paroxysmal blood pressure
  • Absence of obesity

Pheochromocytoma

Diagnosis

  • Plasma metanephrine level
  • Urine free catecholamine
  • Ultrasound/CT
  • MIBG In-111

Cushing's Syndrome

Diagnosis

  • 24-hour urine cortisol
  • 1 mg dexamethasone suppression test (screening)
  • 8 mg dexamethasone suppression test
  • Cortisol circadian rhythm
  • Laboratory tests: Increased hematocrit/hemoglobin, decreased eosinophils
  • Sinus/petrous imaging

Multiple

... Continue reading "Secondary Hypertension and Bariatric Surgery" »

Rehabilitation System: Principles, Goals, and Stages

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*** Constituent Parts of Rehabilitation System: Principle Goals....

- Rehab is the treatment designed to facilitate recovery from injury/disease

- Can be: physical/psychological/social/educational

  • Legal part
  • Medical rehabilitation
  • Vocational rehabilitation
  • Education
  • Compensatory technical, orthopedic means
  • Environmental adaptation
  • Culture, sports, recreation, religion
  • Information
  • Transport
  • Social care and services
  • Income compensation
  • Training of specialists
  • Medical social expertise


^^ Stages of Rehab:

  • I----. Hospital Setting, Hospital Staff
  • II----> In Sanatorium/Outpatient
  • III----> Home Setting, Practitioner or Family Member


^^ Principles, Goals & Task of Rehab:

  • Treatment of Pathology
  • Decrease Impairment
  • Prevent and Treat Complications
  • Increase Activity
  • Physiological
... Continue reading "Rehabilitation System: Principles, Goals, and Stages" »