Cell Biology: Comprehensive Cellular Junctions and Internal Systems
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Cellular Unions and Plasma Membrane Specialization
Specialized regions of the plasma membrane centered in specific proteins are known as cellular unions (or cell junctions). Transmembrane unions are especially important in epithelial tissues.
Classification by Structure
- Zonulae: Completely surround the cell.
- Maculae: Spot-like unions.
Classification by Function
- Occluding Junctions: Their primary function is to close the intercellular space between cells, preventing molecules from passing between them.
- Anchoring Junctions: Connect the cytoskeleton filament of one cell to another or to the extracellular matrix, increasing resistance against strong mechanical tensions. Types include zonulae adherens, maculae adherens (desmosomes), and hemidesmosomes.