Chromosomes, Genes, and Inheritance: A Comprehensive Overview
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Sutton's Chromosome Theory of Inheritance
- Chromosomes occur in pairs.
- Chromosome pairs separate during meiosis.
- Each gamete carries one chromosome from each pair.
- Pairs of chromosomes separate independently of other pairs.
- Fertilization restores the paired condition of chromosomes in the zygote.
Mendel's Laws of Inheritance
- Factors (genes) occur in pairs.
- Factors segregate to form gametes.
- Each gamete carries a single factor.
- Pairs of factors separate independently of other pairs.
- Fertilization restores the paired condition of factors in the zygote.
Chromosomal Abnormalities
Trisomies
- Down Syndrome (Trisomy 21): Congenital mental disability, distinct facial profile, increased risk of illness, and heart defects.
- Patau Syndrome (Trisomy 13): Nerve abnormalities,