Oral Pathology and Systemic Conditions
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Meiosis
2-step cellular division of primitive germ cells (46, diploid) mature germ cells (23, haploid)
Lyon Hypothesis
genetic activity of 1 of the X chromo in each cell of a female embryo; when X chromo in female is inactivated = Barr body forms; X chrome dispersed into nucleus; gross abnormalities
Trisomy 21
Down Syndrome; 3 identical chromo at the same allele; most frequent; fissured tongue; macroglossia, slanted eyes, low IQ, hypodontia
Trisomy 13
poor prognosis; 3 chrom on 13; bilateral cleft lip/palate, microphthalmia/anopthalmia
Karyotype
a photographic representation of of a person’s chromosomal make-up; gross abnormalities
Turner Syndrome
lack X chromosome from father; no Barr bodies on smear; webbed neck, short statue
Klinefelter
extra X chrom... Continue reading "Oral Pathology and Systemic Conditions" »