Protein Structure and Function: From Amino Acids to Polypeptides
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Proteins
∑ - Amino acids are linked together by condensation to form polypeptides.
- Amino acids are then combined to create large polypeptides through condensation reactions which produce many molecules of water (i.e. polypeptides - Hemoglobin and Insulin).
B Skill: Drawing molecular diagrams to show the formation of a peptide bond.
- Basic dipeptide shown to the right. Students should practice drawing with a variety of different amino acids (different “R” groups)
- Every peptide bond should be between the NH2 (amine group) and the COOH (carboxyl group). One H comes from the NH2 and an –OH group comes from the –COOH group to produce H2O
- Condensation reaction
∑ - There are 20 different amino acids in polypeptides synthesized on ribosomes.