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Understanding the Human Heart: Function, Circulation, and Health

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The Human Heart: Anatomy and Function

The heart is an organ about the size of a fist, located in the center of the chest, slightly to the left. It is comprised of two atria and two ventricles. Blood enters the atria through the veins and is driven out of the ventricles through the arteries. The heart has valves that force the blood to circulate in one direction.

The Heartbeat

The beating of the heart is the most noticeable manifestation of its activity. The frequency with which the heart beats varies according to the body's needs. Every heartbeat follows a set of phenomena that constitute a cardiac cycle:

  • Atrial systole: The atria contract and push blood into the ventricles.
  • Ventricular systole: The ventricles contract, and blood leaves through
... Continue reading "Understanding the Human Heart: Function, Circulation, and Health" »

Genetic Engineering and Biotechnology: Applications and Impacts

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Genetic Engineering: Understanding the Building Blocks

Genetic engineering relies on our knowledge of the genetic code, gene regulation mechanisms, transcription, translation, and reduction. Automated sequencing techniques, restriction enzymes, and a set of other tools allow us to split and join DNA fragments. These fragments, when combined with other macromolecular carrier DNA, enable the transfer of genetic information between organisms. These are called recombinant DNA molecules.

Key Processes in Genetic Engineering

  • DNA Transformation: A cell undergoes a genetic change resulting from the entry of a foreign DNA molecule into its core.
  • Transduction: The process of transferring genetic information (e.g., in bacteria) without direct contact, often
... Continue reading "Genetic Engineering and Biotechnology: Applications and Impacts" »

Endocrine and Urinary Systems: Functions and Anatomy

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Endocrine System

We are formed by a series of glands, whose main characteristic is the production of substances called hormones. These hormones, usually discharged into the blood, perform a variety of functions. They regulate the growth, development, and function of many tissues and coordinate the body's metabolic processes. The most important function is to maintain homeostasis. Some of these glands are:

Hypophysis

A small gland housed at the base of the skull in the center of the sphenoid bone (sella turcica). It produces growth hormone and antidiuretic hormone.

Thyroid

A gland in the neck, at the height of the first tracheal rings. It regulates the growth and maturation of tissues.

Parathyroid

There are four glands located in the back of the thyroid.... Continue reading "Endocrine and Urinary Systems: Functions and Anatomy" »

Genetic Fingerprinting, Mutations, and Biotechnology

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Genetic Fingerprint

Genetic fingerprinting is a technique capable of distinguishing and identifying individuals through individual peculiarities in their own DNA.

Mutations

Mutations are alterations in the genetic information of cells that may occur spontaneously in any cell of a living being. Their consequences can be negative, neutral, or harmless, but also advantageous or beneficial.

Gene Mutations

Gene mutations are mutations affecting the nucleotides of DNA.

Chromosomal or Genomic Mutations

Chromosomal or genomic mutations affect chromosome number or structure. They are due to errors in the processes of meiosis. When they affect the whole chromosome, it is called genomics.

Biotechnology

Biotechnology consists of a set of techniques or processes... Continue reading "Genetic Fingerprinting, Mutations, and Biotechnology" »

Understanding Proteins: Structure, Properties, and Classification

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Proteins: Composition and Structure

Proteins consist of carbon (C), hydrogen (H), oxygen (O), and nitrogen (N), and may also contain sulfur (S), phosphorus (P), iron (Fe), magnesium (Mg), and copper (Cu). Proteins are made up of smaller molecules called amino acids, which are linked by peptide bonds.

Amino Acids and Their Properties

Amino acids with uncharged polar side chains are hydrophilic and are usually found on the outside of the cell. Nonpolar side chains tend to aggregate in the interior.

Peptide Bonds and Polypeptides

Amino acids are commonly attached through amide links, called peptide bonds. The union of multiple amino acids results in a peptide. A peptide with fewer than 10 amino acids is called an oligopeptide, and if it contains more... Continue reading "Understanding Proteins: Structure, Properties, and Classification" »

Anabolism: Metabolic Pathways and Carbohydrate Biosynthesis

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Anabolism: The Constructive Phase of Metabolism

Anabolism is the constructive phase of metabolism. It is the set of metabolic pathways whose objective is to obtain more or less complex organic molecules, sharply reduced, from simpler and relatively oxidized ones. Therefore, these are chemical reduction processes.

Features of Anabolic Pathways

  • As we have said, they are basically chemical reduction processes.
  • Reactions are strongly endergonic (energy is needed), for which they use the energy released in catabolic reactions as ATP, NADH, and NADPH.
  • The anabolic pathways for the synthesis of molecules are different from the catabolic ones, although they often share reversible reactions close to equilibrium. There is always some different way on each
... Continue reading "Anabolism: Metabolic Pathways and Carbohydrate Biosynthesis" »

Animal Tissues: Epithelial, Muscle, and Nervous Tissues Explained

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Animal Tissues

Epithelial Tissue

Epithelial tissue consists of sheets of densely packed and connected cells that cover internal and external body surfaces.

Simple Epithelia

Simple epithelia are formed by a single layer of cells that can be:

  • Flattened, like the endothelial walls of capillaries and the lining of blood vessels, which protect yet allow the exchange of substances.
  • Polyhedral (cubic and cylindrical), such as the epithelial lining inside the intestine. Their cells possess microvilli or fingerings on the surface that faces the lumen of the tube.

Stratified Epithelia

Stratified epithelia consist of several layers of cells. Cells in the deepest layer are constantly dividing, and new cells push the older ones upward. The most superficial cells,... Continue reading "Animal Tissues: Epithelial, Muscle, and Nervous Tissues Explained" »

Understanding Vision and Hearing Development in Infants

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Vision Development in Infants

The visual system is designed to capture light effects. The apparatus of global vision allows us to perceive images based on the amount of light reflected. Light enters through the cornea, passes through the pupil to the lens, and is then sent to the retina.

Developmental Milestones

  • Newborn: Distinguishes between light and dark (chiaroscuro).
  • 1 Month: Can stare at a large object.
  • 2 Months: Can accommodate and converge their vision.
  • 3 Months: Can follow a moving object by turning their head.
  • 4 Months: Has a vertical and horizontal visual field of 180 degrees.
  • 6 Months: Acquires eye-hand coordination.
  • 8 Months: Examines objects with more detail.
  • 12 Months: Acquires adult-like visual acuity.

Vision Disorders

Refractive Errors

  • Myopia

... Continue reading "Understanding Vision and Hearing Development in Infants" »

Carbohydrates and Lipids: Structure, Classification, and Functions

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1.2. Carbohydrates and Lipids: Concept, Classification, and Functions

Carbohydrates

Carbohydrates are biomolecules formed fundamentally by C, H, and O in the proportion CnH2nOn. Hence, H and O are in the same proportion as in water (H2O), also called hydrates of carbon. Carbohydrate molecules are chains formed by carbon atoms attached to radical groups and hydroxyl (OH) groups. There may be an alcoholic or a carbonyl group; this group may be an aldehyde (gluc aldose) or a ketone (gluc ketonic). For this reason, they are defined as polyhydroxyaldehydes or polyhydroxyketones.

Classification:

Carbohydrates are classified in two forms:

  1. According to the functional group they possess:
    • Ketoses: if they have ketone groups.
    • Aldoses: if they have aldehyde groups.
... Continue reading "Carbohydrates and Lipids: Structure, Classification, and Functions" »

DNA Transcription: Process, Elements, and Stages

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Elements Involved

In order to perform the transcription of DNA into cells, the following elements are required:

  • Original DNA to serve as a template to be copied.
  • RNA polymerase: synthesizes RNA from a DNA template.
  • Ribonucleotide triphosphates to perform the copy.
  • Poly-A polymerase, small nuclear ribonucleoprotein, RNA ligase.

Transcription Mechanism

As in replication, there are differences between prokaryotes and eukaryotes. The main differences are the existence of multiple RNA polymerases in eukaryotes and, above all, the need to produce a "mature" form of some RNAs due to the existence of introns. The process is divided into three stages:

  • Initiation: The RNA polymerase binds to a region of DNA prior to the DNA that is to be transcribed. It then
... Continue reading "DNA Transcription: Process, Elements, and Stages" »