Notes, summaries, assignments, exams, and problems for Biology

Cerebral and Basilar Arteries

The carotid artery supplies 80% of the oxygen to the cerebral hemispheres. The two internal carotid arteries branch into the middle cerebral arteries, which provide 60% of the brain's oxygen supply. The anterior communicating artery connects the right and left middle cerebral arteries.

Two vertebral arteries (left and right) ascend along the spinal cord and merge at the base of the skull to form the basilar artery. This artery supplies the medulla, pons, and other brainstem structures.

Circle of Willis

1. Frontal lobes
2. Temporal lobes
3. Middle cerebral artery (right and left)
4. Anterior cerebral artery
5. Posterior cerebral artery
6. Basilar artery
7. Vertebral arteries (right and left)
8. Spinal cord
9. Internal carotid artery
10. Anterior communicating

Cytokinesis

Cytokinesis begins in anaphase and continues through telophase.

• In animals: The process involves strangling the cytoplasm. Segmentation is a linear division, resulting in the formation of a contractile ring formed by actin filaments.
• In plants: The cell wall prevents segmentation. This is done by forming a new wall inside the cell. This new wall is formed at the equator by the association of Golgi apparatus vesicles and microtubules, and it is called a phragmoplast. It extends laterally to reach the cell wall.

Types of Cell Division

1. Bipartition

   Division of the cell. Two daughter cells originate, equal in size. The process involves karyokinesis and cytokinesis, with its variant being strangulation.

2. Multiple Fission

   Divisions of the cell.

Understanding Key Health Concepts

1 - Life expectancy is the average number of years a person born in a particular country in a specific year is expected to live, assuming mortality rates remain constant.

2 - According to the WHO, health can be defined as: "A state of complete physical, mental, and social well-being, and not merely the absence of disease or infirmity."

3 - CVD stands for cardiovascular diseases, which affect the heart or blood vessels.

4 - Myocardial infarction, a type of coronary heart disease (CHD), results in the death of myocardial tissue and permanent damage to the heart muscle. Angina pectoris occurs when a partial blockage reduces blood flow to an area of the heart, causing pain but not irreversible damage. Heart attacks... Continue reading "Understanding Key Health Concepts: A Concise Overview" »

Staphylococcus

• Easily develops antimicrobial resistance
• Gram-positive cocci
• Catalase-positive
• Facultative anaerobes
• Not demanding in their nutritional requirements
• Grow in normal media
• Some pathogenic species are generally opportunistic pathogens, commensals
• Important in animal and human infections

Natural Habitat

Widespread in nature; found on human and animal skin, surfaces of objects, air, soil, water, and milk.

S. aureus

Main pathogen associated with infections; colonizes nasal passages and pharynx.

S. epidermidis

Produces skin lesions, wound infections; microbiota found in the skin, respiratory tract, and gastrointestinal tract.

S. saprophyticus

Associated with urinary tract infections.

Immunogens

• Polysaccharide A (specific for S. aureus)
  • Antiphagocytic
  • Antiplatelet
  • Activator

Forensic Aspects of Asphyxia

Carotid Artery Occlusion

Loss of consciousness typically occurs within 10-15 seconds of complete occlusion of the carotid arteries. This timeframe allows for the implementation of restraint mechanisms.

Differential Diagnosis at the Scene

Differential diagnosis is crucial and is made at the scene, considering:

• The victim's clothing state.
• Presence of extracervical lesions indicative of control or struggle.
• Severity of neck injuries.

The diagnosis of accidental etiology is based on a meticulous examination of the scene. A high blood alcohol level may explain the victim's low resistance or the possibility of accidental strangulation.

Forensic Pathology of Submersion (Drowning)

Definition and Types of Submersion

Death or pathological... Continue reading "Forensic Pathology: Asphyxia and Drowning Investigations" »

The Nervous System

Consisting of two types of cells:

• Neurons: consist of neuronal bodies, Dendrites (extensions where the nerve impulse enters the body), and axons.
• Glia (or Neuroglia): Made by the supporting structure of the nervous system, they collaborate in nutrition and feeding of neurons.

Nervous System Division

Central Nervous System (CNS), peripheral nervous system, autonomic (or vegetative) nervous system.

Central Nervous System

Comprising:

• Brain: Located in the skull, it consists of an internal gray substance and an external white substance. Surrounded by 3 membranes called meninges: Piamater, Arachnoid, Dura mater.

Parts:

• Cerebrum: Divided into hemispheres (left and right), weighing between 1200 and 1600g. It includes frontal, parietal, occipital,

Lung Cancer Impact: Eastern Europe and North America have the highest lung cancer incidence rates. Men are disproportionately affected, with rates 76% higher in men than in women in Eastern Europe and 69% higher in North America. However, incidence in women is increasing. The 5-year survival rate remains very low.

Risk Factors: Smoking accounts for a substantial portion of lung cancer deaths: 80% in men, 75% in women, and contributes to 17% of lung cancer cases in non-smokers. Smoking is also linked to 28% of all cancer deaths. Other risk factors include asbestos, radon exposure (mining or environmental), a diet low in vitamins A, C, E, and beta-carotene, as well as genetic and familial factors.

Lung Cancer Control: Effective control strategies... Continue reading "Lung Cancer: Incidence, Risks, and Diagnosis" »

Understanding Health and Well-being

Health is a state of complete physical, mental, and social well-being, and not merely the absence of disease.

Health depends on individual lifestyle and personal behavior, including physical activity, environmental and social factors such as climate and pollution, and genetic information.

Myocardial Infarction (Heart Attack)

When blood flow through a vessel of the heart is blocked, blood stops flowing to an area of heart muscle, halting the supply of oxygen and nutrients. This leads to muscle tissue death and permanent heart damage. If the blockage is partial and reduces blood flow, it causes a sharp pain known as angina.

Symptoms of a Heart Attack

Symptoms start with pain or discomfort in the center of the chest,... Continue reading "Understanding Health, Heart Attacks, and Risk Factors" »

How Infectious Diseases Spread

Infectious diseases can spread through various means:

• Water: Consuming water contaminated with feces from humans or animals.
• Food: Eating fruits and vegetables irrigated with contaminated water or improper food handling.
• Animals: Through disease vectors. For example, the Anopheles mosquito transmits malaria.

Stages of Infectious Disease Development

The development of infectious diseases involves several stages:

• Infection: The organism enters the body.
• Incubation Period: The time from infection to the appearance of symptoms.
• Period of Manifestation: The disease is fully manifested, with symptoms like fever and pain.
• Period of Decline: Symptoms subside due to the immune system and medications.
• Convalescence: The patient recovers

Understanding Circulation and Blood Disorders

Pulmonary and Systemic Circulation

Pulmonary Circulation: Circulation through the lungs.

Systemic Circulation: Circulation to the rest of the body.

Vena Cava: Carries deoxygenated blood.

Coronary Heart Disease

Coronary Heart Disease: Refers to any disease that results in blockage of the coronary blood supply to part of the heart's muscular wall. The blockage causes partial deprivation of oxygen to the affected part and may result in the death of muscle cells.

Effects of Coronary Heart Disease

If a large part of the heart is affected, the person may die instantly. If a small region is affected, it may recuperate.

Atherosclerosis

Atherosclerosis: The most common form of hardening of the arteries. It begins... Continue reading "Understanding Pulmonary and Systemic Circulation & Blood Disorders" »