Notes, summaries, assignments, exams, and problems for Biology

Essential Molecular Biology Q&A

Nonsense Mutation Severity

Why is a nonsense mutation usually a severe change? (The polypeptide now stops translation at a different location.)

Virus Multiple Choice

A virus _____ (all of the above)

Telomere Definition

A telomere is _____ (the end of a eukaryotic chromosome)

Intron Function

An intron _____ (is the mRNA sequence removed and not used to code for amino acids)

CRISPR-Cas System

The CRISPR-Cas system _____ (is a prokaryote defense against a virus)

DNA Duplication Term

_____ refers to making a duplicate copy of DNA in a cell (replication)

Virus Host Range

Most viruses can infect _____ (a narrow range of species)

Viral Nucleic Acid with Uracil

A virus nucleic acid is found to include uracil. This means that its

Human Beings and Health

The World Health Organisation (WHO) defines health as 'the complete physical, mental and social well-being, not only the absence of disease'.

Factors that Influence Health

The environment: healthy surroundings should be free of biological, physical or chemical elements that are harmful to your health.
Personal characteristics: genetic factors, age and gender predispose people to suffer from certain types of illnesses.
Lifestyle: healthy habits and lifestyles are very important for staying healthy.
Healthcare: it is essential to have an efficient healthcare system to guarantee public health.

Vital Signs

Vital signs are physiological parameters that inform us of our state of health or the evolution of a disease.

White Matter:

Formed by neurons' axons, white matter acts as communication cables and the connection between control centers.

Brain:

Part of the central nervous system found within the cranium, the brain weighs 1.4kg and is the largest organ in our body. It serves as the center of integration and consciousness. The brain is organized with grey matter making up the outer surface and white matter in the interior. Cranial nerves emerge directly from the brain, which is part of the peripheral nervous system.

Parts of the Brain:

• Cerebellum:

  The largest part of the brain, consisting of hemispheres, the corpus callosum, the hippocampus, the thalamus, and the hypothalamus.

• Hypothalamus:

  The master gland of the endocrine system, controlling most of its activity.

Question 1:

Group the following as nitrogenous bases and nucleosides:

• Adenine, Cytidine, Thymine, Guanosine, Uracil and Cytosine.

Answer

Nitrogenous bases present in the list are adenine, thymine, uracil, and cytosine.

Nucleosides present in the list are cytidine and guanosine.

Question 2:

If a double stranded DNA has 20 per cent of cytosine, calculate the per cent of adenine in the DNA.

Answer

According to Chargaff’s rule, the DNA molecule should have an equal ratio of pyrimidine (cytosine and thymine) and purine (adenine and guanine). It means that the number of adenine molecules is equal to thymine molecules and the number of guanine molecules is equal to cytosine molecules.

% A = % T and % G = % C

If dsDNA has 20% of cytosine, then according to... Continue reading "Understanding DNA: Bases, Replication, and Functions" »

Genetics: Key Concepts

Vocabulary Terms:

• Chromosome: A structure of nucleic acids and protein found in the nucleus of most living cells, carrying genetic information in the form of genes.
• Gene: A unit of heredity transferred from parent to offspring, determining some of the offspring's characteristics.
• Homologous Pairs: Chromosomes containing genes for the same traits but potentially different alleles. These are usually paired during mitosis.
• Allele: One of two or more alternative forms of a gene that arise by mutation and are found at the same location on a chromosome.
• Sister Chromatid: Identical copies of a chromosome formed by DNA replication, joined by a common centromere. It's essentially half of a duplicated chromosome.
• Nucleotide: A compound

• The outer ear: it is formed by the pinna and the auditory canal.
• The middle ear: a cavity in the eardrum that reaches the oval window and the round window.
• The inner ear: formed by the membranous labyrinth.
• Sweat gland: this secretes sweat, cooling the body surface when it is necessary and removing certain waste substances.
• Sebaceous gland: these secretes substances that lubricate the skin and hair.
• Taste buds: are located inside the mouth especially on the tongue.
• Long bones: these are long and contain spongy bone tissue at either end, as well as compact bone.
• Short bones: these are rounded and mostly made up of spongy bone tissue.
• Flat bones: these are plate-shaped. Formed by an inner layer of bone tissue surrounded by two layers of compact bone

Step 1: Glycolysis - What Happens?

1 glucose molecule is split into two 3-carbon molecules called pyruvate.

Who Controls It? Enzymes. Where? Cytosol. Result? Two molecules of ATP are produced.

Step 2: Oxidative Respiration - The pyruvate molecules made during glycolysis still have a lot of potential to make more energy (ATP). What Happens? The 2 pyruvate molecules now go through oxidative respiration where they produce carbon dioxide, water, and 34 ATP! Where? Mitochondria.

Three Metabolic Pathways - Within these two systems, aerobic vs. anaerobic, there are three main metabolic pathways by which ATP energy reserves are restored.

1. The ATP-PC Pathway: Anaerobic Alactic.

2. The Glycolysis Pathway: Anaerobic Lactic.

3. Cellular Respiration: Aerobic - It is

Environmental Factors

Characteristics of the environment that affect living things are called environmental factors. They can be abiotic (related to non-living things) or biotic (related to living things).

Biotic and abiotic factors

⦁ Abiotic factors: Physical and chemical conditions that affect living things.

The main abiotic factors are water, light, temperature, soil, pH, humidity, and nutrients found in water and soil. Some abiotic factors are more important than others depending on the location they are in.

• Sunlight is essential for life on Earth to exist.
• The concentration of oxygen in the atmosphere decreases as altitude increases.
• Temperature is a decisive factor in the physiological activity of living things.
• Water is an essential substance

Core Concepts of Health and Disease

Health and Disease Definitions

• Health: A state of complete physical, mental, and social well-being, and not merely the absence of disease or infirmity.
• Disease: A disorder or malfunction of the mind or body, which leads to a departure from good health. It can be a disorder of a specific tissue or organ due to a single cause.

Pathogens and Infectious Diseases

Types of Pathogens

• Fungi
• Bacteria
• Viruses

Diseases Caused by Viruses

Influenza (Flu)

Influenza is a virus that causes a severe form of respiratory tract infection with generalized bodily symptoms. While it shares cold-like symptoms, its onset is rapid and violent, often featuring:

• High fever
• Severe aches and pains, often in the back and muscles

Other common viral diseases... Continue reading "Understanding Disease, Immunity, and STIs: Core Concepts" »