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Cell Biology: Structure, Function, and Chemical Reactions

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Cell Organization and Structure

Cells in Humans (Eukaryotic Cells)

Cell Membrane

The outermost membrane, a lipid bilayer, controls what enters and exits the cell. This structure is also used in vaccine production to hold mRNA.

Mitochondria (Mitochondrion)

The powerhouse of the cell, responsible for ATP (Adenosine triphosphate) production. The ATP production rate depends on the folds of cristae. Some cells, like liver cells, have multiple mitochondria. The mitochondrion contains a matrix, a thick liquid with a high concentration of enzymes that facilitate ATP production.

Lysosome

The cell's recycle bin.

Golgi Apparatus

Packages proteins for transport in and out of cells.

Rough Endoplasmic Reticulum

Creates proteins.

Smooth Endoplasmic Reticulum

Creates... Continue reading "Cell Biology: Structure, Function, and Chemical Reactions" »

Human Eye Structure and Function: A Detailed Look

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Human Eye Structure and Function

Key Components:

  • Conjunctiva: Thin, transparent membrane lining the front of the sclera. It's moistened by tears, produced in the tear glands, which contain lysozyme, an enzyme that kills bacteria.
  • Pupil: Opening in the iris through which light passes. It controls the amount of light entering the eye and appears black due to the black pigment of the choroid.
  • Lens: Clear structure that allows light into the eye. It's made of stiff jelly and can change shape to focus light.
  • Iris: Colored part of the eye that responds to light.
  • Cornea: Transparent, protective layer at the front of the eye.
  • Suspensory Ligaments: Fibers supporting the lens. When pulled tight, the lens is thin; when loosened, the lens is thicker.
  • Ciliary Muscles:
... Continue reading "Human Eye Structure and Function: A Detailed Look" »

Ecology: The Study of Organism Interactions and Adaptations

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Ecology

The scientific study of how organisms interact with each other and with their non-living environment.

Ecological Niche

The manner in which an organism uses the resources in, and is influenced by the conditions of its habitat.

Habitat

The physical place, or type of place, where an organism lives.

Physical Adaptation

Genetically-inherited characteristics that enable a given organism to survive and reproduce using a given niche.

Niche Partitioning

The division of niches between species so as to cut down on competition.

Resource

A material that is used, and potentially used up.

Environmental Conditions

Background features of the habitat.

Fundamental Niche

The largest array of resources an organism can utilize.

Realized Niche

The actual set of resources... Continue reading "Ecology: The Study of Organism Interactions and Adaptations" »

Epithelial and Connective Tissues: Functions and Locations

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Epithelial Tissue Types

Simple Squamous Epithelium

Function: Reduces friction; controls vessel permeability; performs absorption and secretion.

Locations: Mesothelia lining pleural, pericardial, and peritoneal cavities; endothelia lining heart and blood vessels; portion of kidney tubules (thin sections of nephron loops); inner lining of cornea; alveoli of lungs.

Stratified Squamous Epithelium

Function: Provides physical protection against abrasion, pathogens, and chemical attack.

Locations: Surface of skin; lining of mouth, throat, tongue, esophagus, rectum, anus, vagina.

Simple Cuboidal Epithelium

Locations: Glands, ducts, portion of kidney tubules, thyroid gland.

Stratified Cuboidal Epithelium

Function: Protection, secretion, absorption.

Locations:... Continue reading "Epithelial and Connective Tissues: Functions and Locations" »

Functions of Cell Organelles

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Nucleus:

Converts genetic material, controls all the cell, and contains nucleolus.

Mitochondria:

Converts solar energy in food to usable compounds.

Chloroplast:

Converts solar energy to chemical energy stored in food.

Cytoskeleton:

Maintains cell shape and helps cell move.

Ribosomes:

Synthesize proteins.

Endoplasmic Reticulum:

Assembles proteins and lipids.

Vacuoles and Vesicles:

Store materials.

Centrioles:

Organize cell division.

Cell Membrane:

Regulates materials that enter and leave the cells.

Golgi Apparatus:

Packages proteins and lipids for storage or transport out of the cell.

Cell Wall:

Shapes, supports, and protects cell.

Lysosomes:

Break down and recycle macromolecules.

Cytoplasm:

Gel-like mixture, surrounded by cell membrane, contains hereditary... Continue reading "Functions of Cell Organelles" »

Understanding the Human Brain and Nervous System

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Thalamus

Regulates communication between several parts of the brain and the endocrine system.

Corpus Callosum

Structure made of nerves that bridges two hemispheres.

Hippocampus

Part of the limbic system, responsible for long-term memory.

Cerebellum

Responsible for motion, balance, and new learning. Exterior grey matter, interior grey matter.

Brainstem

Several regions including medulla oblongata (elongates into the spinal column). Location of several centers of involuntary nervous control.

Hypothalamus

Master gland of the endocrine system, controlling most of its activity.

Two Cerebral Hemispheres

Surfaces known as cerebral cortex and comprised of grey matter. Folder structure made of rounded gyri and recessed sulci divide the lobes.

Spinal Cord

Brings messages... Continue reading "Understanding the Human Brain and Nervous System" »

From Protocells to Species: Understanding Chemical and Biological Evolution

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Chemical Evolution


Chemical evolution refers to the processes that created molecules that make up living things (biomolecules), and then formed structures called protocells.

Biomolecules Were Created

(Simple organic molecules) - Biomolecules were synthesized when the components of Earth's primitive atmosphere reacted on contact with each other.

More and More Complex Biomolecules Were Created

From the simple molecules in the "primordial soup."

Protocells Were Formed

When the biomolecules became organized in spherical membranes, with proteins and nucleic acids inside them.

Biological Evolution

Biological evolution refers to the processes that led protocells to become different types of cells and resulted in all the different organisms ever to have inhabited
... Continue reading "From Protocells to Species: Understanding Chemical and Biological Evolution" »

It used to define the member functions of a class outside

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DESARROLLO INMUNOLOGY 2015

  1. About the killing mechanism of Tc cells (the Kiss of death)

    • How would you define it?

      It is a killing attack deliver by an armed cytotoxic T cell previously sensitize by the same antigen. A single Tc cell can attack many target cells (second amplification of the celular IR), we have to take into account that the contact between cells (during the Kiss of death) is very short in time. This attack ends with the death of infected cells.

    • How many activating signal needs a T cell to be able of delivering the Kiss of death. Explain details for each signal?
      They need 3 signal:
      1o→recognition of the appropiate peptide loaded onto a self HLA- classmolecule.

      2o→co-stimulatory signal delivered by CD28 bound to its ligand on

... Continue reading "It used to define the member functions of a class outside" »

Evidence of Evolution: Understanding Natural Selection and Adaptation

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Artificial Selection and Evolution

Possible Misconceptions

  • Populations evolve, not individual organisms. Individuals may have certain heritable variations, but they do not evolve these traits during their lifetime.

Evidence of Evolution

The Study of Fossils

Support for Evolution

  • Charles Darwin proposed a possible explanation for the origin of species, explaining various data and suggesting areas for further research.
  • The theory of evolution suggests that all organisms on Earth share a common ancestor.

Fossil Record

  • Fossils provide significant evidence of evolutionary change, offering a record of species that existed long ago.
  • Ancient species often show similarities to species living today.
  • Not all extinct fossils have modern counterparts, and some ancient
... Continue reading "Evidence of Evolution: Understanding Natural Selection and Adaptation" »

Understanding Rheumatic Fever: Causes, Symptoms, and Complications

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Rheumatic Fever

Is a multisystem inflammatory disease that can involve the heart, joints, skin, and brain. The disease develops after a streptococcal infection (A beta-hemolytic – Streptococcus pyogenes) – mostly pharyngitis

Clinical Features

  • Occur most often in children
  • Develop 2-4 weeks after streptococcal infection
  • Fever, malaise, and increased erythrocyte sedimentation rate
  • Rheumatic heart disease – pancarditis; inflammation of the entire heart (3 layers)

Pericarditis

Leads to serous effusions

Myocarditis

Leads to cardiac failure

Endocarditis

Leads to valvular damage

  • Rheumatic endocarditis – mitral and aortic valves (mostly); the valves become thickened, fibrotic, deformed, & calcification (may)
  • Joint involvement – arthralgia, arthritis,
... Continue reading "Understanding Rheumatic Fever: Causes, Symptoms, and Complications" »