Acute Renal Failure: Signs, Classification, and Diagnosis
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Acute Renal Failure (ARF)
Signs
ARF is often asymptomatic. However, some common signs include:
- Oliguria: Urine output of less than 400 ml per day
- Increased nitrogen products in the blood
- Electrolyte and acid-base abnormalities
Classification of Acute Renal Failure
1. Pre-renal ARF
This type accounts for 55% of cases. It is characterized by a deficiency in kidney perfusion, which decreases the glomerular filtration rate (GFR). There is no frank damage to the renal parenchyma initially.
Features of Pre-renal ARF:
- Often reversible
- No initial damage to the renal parenchyma
- Prolonged deficiency can lead to ischemia and acute tubular necrosis
- The renal tubules and loop of Henle are most affected by ischemia
Phases of Pre-renal ARF:
- Extension phase: Swelling occurs,