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Understanding Bone Formation and Craniofacial Growth

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Bone Formation Processes

Intramembranous Bone Formation

Bone forms via the direct secretion of bone matrix within connective tissue, without any intermediate formation of cartilage. There is no formation of cartilage in this process.

Key characteristics:

  • Occurs in the periosteum (external part), endosteum, alveolar bone, and sutures.
  • In the craniofacial vault complex, this type occurs specifically in the cranial vault and jaws.

Endochondral Bone Formation

In this process, cartilage is converted into bone.

Key characteristics:

  • In early stages, cartilage is present from the nose to the cranial base and occipital bone.
  • Prenatally, a series of synchondroses exist within and between the ethmoid, sphenoid, and occipital bones. These facilitate rapid increase
... Continue reading "Understanding Bone Formation and Craniofacial Growth" »

Genetics: Transcription, Translation, and Genetic Code Principles

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True or False Statements:

a) Transcription and translation occur in the nucleus.

TF

b) During transcription, an RNA molecule is formed.

TF

c) Each RNA molecule can carry any amino acid.

TF

Characteristics of the Genetic Code

  • Universality: The specificity of the genetic code has been conserved from very early stages of evolution.
  • Degenerate: A particular codon always codes for the same amino acid.
  • Specificity: Each codon corresponds to a single amino acid.
  • Nonoverlapping and Commaless: The code is read from a fixed starting point as a continuous sequence of bases, taken 3 at a time.

Amino Acid Calculation:

The shortest gene discovered in human chromosome 19 consists of 1000 nucleotides, 666 nucleotides of which are introns. What is the maximum number of... Continue reading "Genetics: Transcription, Translation, and Genetic Code Principles" »

Cell Membrane Dynamics and Transport Mechanisms

Classified in Biology

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Cell Membrane Dynamics

Plasma membrane phospholipids are labeled with a fluorescent tag and then the phospholipids in one area are bleached with a laser beam to eliminate the fluorescent signal. What would one observe after the cell is incubated for a few minutes? The bleached molecules would diffuse laterally through the membrane and intermix with unbleached molecules. Cellular membranes are mosaic and fluid. Glycosylated proteins and lipids within the plasma membrane are important for cell recognition and protection.

Passive Diffusion

Passive diffusion is a spontaneous process. Water diffuses through certain organs such as the kidneys and bladder much faster than would occur by passive diffusion through a lipid bilayer alone. What accounts for... Continue reading "Cell Membrane Dynamics and Transport Mechanisms" »

Human and Plant Biology: Homeostasis, Thermoregulation, Blood Sugar, and Tropisms

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Still the Eye

Cornea Lens: More spherical lens with shorter focal length
Thinner lens with longer focal length (requires less refraction)
Suspensory Ligaments: Distant = flat; Near = round/thick

Homeostasis

Homeostasis: Maintenance of a constant internal environment despite changes in surroundings.
Control Center: The hypothalamus in the brain decides on the appropriate response. Receptors: In the skin and brain, detect changes in the body. Effectors: E.g., sweat glands, body hair, and thyroid glands change to increase/decrease body temperature.

Thermoregulation

Thermoregulation: If the body is too cold or hot, body temperature is adjusted to what it should be (negative feedback mechanism). It involves receptors linked to the hypothalamus, which
... Continue reading "Human and Plant Biology: Homeostasis, Thermoregulation, Blood Sugar, and Tropisms" »

Zika Virus: Transmission, Symptoms, and Prevention

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Zika is a mosquito-borne disease transmitted by the same mosquito that carries the dengue virus. There have also been cases of transmission through sexual intercourse.

Transmission

Most people get Zika from a mosquito bite. Mosquitoes become infected when they feed on the blood of a person already infected with the virus, and when they bite others, they can transmit the virus. Other forms of transmission include:

  • A pregnant woman can pass the Zika virus to her fetus during pregnancy or at the time of birth.
  • Zika can also be transmitted through sexual intercourse and blood transfusion.

Symptoms

Zika can cause incomplete brain development in fetuses. Common symptoms include fever, rash, joint pain, and conjunctivitis.

Prevention

To reduce the risk of

... Continue reading "Zika Virus: Transmission, Symptoms, and Prevention" »

Woman called Donna Truhana

Classified in Biology

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SPERMATOZOA 

Spermatozoa, or male gametes, are small, mothie cells (capable of movement). They carry the hereditary information from the father.
-The head, which contains the cell nucleus with the hereditary material
-A mid-piece, the many mitochondria of which generate the enrgy required for movement.
-The tail, which is called flagellum, enables them to move.
THE FORMATION OF SPERMATOZOA
The formation of spermatozoa, takes place in the seminiferous tubules, which include the interstitial cells that segretate testosterone. The walls of these tubules contain cells called germ cells, which are constantly multiplying themselves. As they multiply, the cells move towards the end of the tube and gradually mature until they become spermatozoa. The process
... Continue reading "Woman called Donna Truhana" »

Sensory Systems and Nervous Coordination

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Receptors

Internal receptors perceive changes inside the body, such as a rise in blood pressure. External receptors perceive stimuli in the external environment.

Types of Receptors

  • Mechanoreceptors: Perceive mechanical stimuli (pressure).
  • Thermoreceptors: Perceive changes in temperature.
  • Chemoreceptors: Detect chemical substances in the air, water, etc.
  • Nociceptors: Perceive pain stimuli.
  • Photoreceptors: Light sensitive.

Nervous System

The nervous system analyzes internal and external stimuli perceived by receptors, generating responses. It carries out this function through nerve impulses transmitted by cells called neurons. This system coordinates fast, short-lived responses (e.g., muscle contraction).

Endocrine System

The endocrine system is made up... Continue reading "Sensory Systems and Nervous Coordination" »

Internal leakage in

Classified in Biology

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Sensory receptors are responsible for perceiving infortion, which they convert into a nerve impulse. The nerve impulse travels to the brain and produces a feeling.

Photoreceptors: they detect light stimuli and are located in the eye. Some of them respond to dim light conditions and produce black and white vision; others respond to bright light and produce colour images.
Mechanoreceptors: they are stimulated by mechanical changes such as pressure, contact or sound waves. They are several receptors in the skin, muscles and joints. Auditory receptors are included in this group.
Chemoreceptors: they respond to chemical changes. Taste and smell receptors belong to this group.
Thermoreceptors: they detect temperature changes. Some skin receptors are
... Continue reading "Internal leakage in" »

Exercise Physiology: Antioxidants, Fatigue, and Body Composition

Classified in Biology

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Antioxidants and Exercise

Key antioxidants include Vitamin C, Vitamin E, Carotenoids, Glutathione (GSH), and Coenzyme Q10 (Q10).

Enzymatic Antioxidant Systems

  • Superoxide Dismutase (SOD)
  • Catalase
  • Glutathione Peroxidase

Functions of Antioxidants

  • Neutralize free radicals by donating electrons (e-) and hydrogen ions (H+).
  • Decrease lipid peroxidation both at rest and after exercise.
  • Note: Supplementation may not necessarily decrease overall oxidative stress markers.
  • Note: Vitamin E supplementation does not appear to decrease neutrophil count after exercise.

Benefits and Roles of Oxidative Species

  • Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) are important for cellular development, function, and as stimuli (cellular messaging) – involved
... Continue reading "Exercise Physiology: Antioxidants, Fatigue, and Body Composition" »

The Cardiovascular System: Pulmonary and Systemic Circulation

Classified in Biology

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Two Main Circuits of the Cardiovascular System

Pulmonary Circulation

Pulmonary circulation refers to the circulation of blood in which deoxygenated blood is pumped from the heart to the lungs and oxygenated blood is returned back to the heart. Pulmonary circulation only occurs between the heart and the lungs.

Systemic Circulation

Systemic circulation refers to the circulation of blood in which oxygenated blood is pumped from the heart to the body and deoxygenated blood is returned back to the heart. Systemic circulation occurs between the heart and the entire body.

Pericardial Sac

The pericardial sac is the outermost layer of the heart. It surrounds the heart and protects it.

Heart Valves

Atrioventricular (AV) Valves

The AV valves prevent backflow into... Continue reading "The Cardiovascular System: Pulmonary and Systemic Circulation" »