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Viral Reproduction and Infection Mechanisms

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Extracellular is inactive DNA or RNA surrounded by proteinIntracellular – active inside a host cell/ viral reproductionprotein capsid - Viral nucleic acid presentcapsomere- protects genetic materialretroviruses: ss RNA hepadnaviruses: dsRNA enveloped”- membrane lipid bilayer (host)& proteins (virus)naked-+ viral DNA complex viruses- icosahedral head/ helical tail/ Tail fibers attach to host cellviral replication: the virion attaches host specific/ proteins interact w/ receptors on surface/ if receptor not present= can’t infect. 2. Phages often complex3.active/intracell/ production of new virions/ viral mRNA is required SS DNA ->DS DNA -> mRNA / DS DNA= mRNA (w/polymerase) RNA polymerase” to make mRNA from viral RNA/ SS RNA

... Continue reading "Viral Reproduction and Infection Mechanisms" »

Enzymes, Cellular Respiration, and Genetics: Key Concepts

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Key Concepts in Enzymes, Cellular Respiration, and Genetics

1. Free Energy Curve

In a catalyzed reaction, the enzyme lowers the activation energy required for the reaction, making it proceed more quickly. The free energy curve for the catalyzed reaction is shifted to the left compared to the uncatalyzed reaction.

2. Components in a Chemical Reaction

  • Reactants: A and B
  • Products: C and D (catalyzed)

3. Factors Affecting Enzyme Function

  • Temperature: Enzymes have an optimal temperature; deviation can denature them.
  • pH: Enzymes function best within a specific pH range.
  • Substrate Concentration: Up to a point, increasing substrate concentration increases enzyme activity.

4. Definition of an Enzyme

Enzymes are biological catalysts that accelerate chemical reactions... Continue reading "Enzymes, Cellular Respiration, and Genetics: Key Concepts" »

Barrera.

Classified in Biology

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Barrera especifica: Acciones que realiza el sist. inmunitario que se pone en funcionamiento cuando el organismo no ha podido evitar la invacion del agente patogeno. hace que la persona adquiera inmunidad. FAGOSITOS.
Barrera inespecifica: son iguales para todos los agentes patogenos y actuan de forma indiscriminada frente a cualquiera de ellos.
1º barrera: evita entrada de germenes. estructural-piel-mucosas-lagrimas-saliva-jugos gastricos-secreciones acidas.
es inespecifica----> intenta que ninguna noxa ingrese, no deja memoria inmune.
2º barrera o respuesta inflamatoria: impide que las noxas que ingresan causen infeccion.(inflamacion-dolor-rubor-color)
Sangre->globulos blancos o leucocitos= fagocitan cualquier noxa.
             ... Continue reading "Barrera." »

Understanding Cellular and Acquired Immunity: Types, Mechanisms, and Pathologies

Classified in Biology

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Cellular Immunity

Cellular immunity involves two main types of lymphocytes: T lymphocytes and B lymphocytes. It also involves non-T, non-B cells. This system effectively destroys:

  • Foreign cells
  • Tumor cells
  • Virus-infected cells
  • Cells infected by intracellular pathogens

T Lymphocytes

T4 Lymphocytes

TH Lymphocytes: These cells stimulate other T cells and B lymphocytes.

TD Lymphocytes: These cells increase the number and activity of macrophages.

T8 Lymphocytes

TC Lymphocytes: These cells destroy target cells.

TS Lymphocytes: These cells regulate and suppress excessive or inappropriate immune responses. They deactivate lymphocytes once antigenic agents are controlled.

A phagocyte captures a foreign element, digests it, and presents it as an antigen-presenting... Continue reading "Understanding Cellular and Acquired Immunity: Types, Mechanisms, and Pathologies" »

Circulatory and Excretory Systems: Structure and Function

Classified in Biology

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Circulatory System Elements

The circulatory system includes:

  • Veins, arteries, and capillaries: These vessels transport blood throughout the body.
  • Heart: This organ pumps the blood.

Arteries vs. Veins

Arteries and veins differ in structure and function:

  • Arteries: Have thick, elastic walls that stretch and spring back, propelling blood forward. They carry blood away from the heart.
  • Veins: Have thinner walls that cannot stretch as much. They often have valves to prevent the backflow of blood, carrying blood to the heart.

Capillary Structure and Function

Capillaries form a network connecting arteries and veins throughout the body. Their walls are only one cell thick, facilitating the diffusion of nutrients and oxygen into tissues. This process occurs via... Continue reading "Circulatory and Excretory Systems: Structure and Function" »

Neck and Pelvic Anatomy Essentials

Classified in Biology

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Neck Anatomy

The head and neck join the upper chest. The neck comprises skin, fibrous muscles, major vascular elements, lymph nodes, organs (cervical larynx, cervical trachea), and glands (thyroid and parathyroid).

The skeletal neck includes the cervical spine.

  • Platysma (2): Thin ring from the superclavicular zone to the face, deep chin.
  • Sternocleidomastoid (2): Lateral neck, from the thorax to the temporal and occipital mastoid bones.
    • Origin: Lower insertion and command of the sternum and below the clavicle.
    • Lateral/External: External jugular vein, ending with the subclavian, used for serum.
    • Medial/Internal: Vasculo-nervous bundle, primitive carotid artery, internal jugular vein, neurogastric nerve.
    • Double Innervation: Branches of the nerve cord and
... Continue reading "Neck and Pelvic Anatomy Essentials" »

Acute Renal Failure: Signs, Classification, and Diagnosis

Classified in Biology

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Acute Renal Failure (ARF)

Signs

ARF is often asymptomatic. However, some common signs include:

  • Oliguria: Urine output of less than 400 ml per day
  • Increased nitrogen products in the blood
  • Electrolyte and acid-base abnormalities

Classification of Acute Renal Failure

1. Pre-renal ARF

This type accounts for 55% of cases. It is characterized by a deficiency in kidney perfusion, which decreases the glomerular filtration rate (GFR). There is no frank damage to the renal parenchyma initially.

Features of Pre-renal ARF:

  • Often reversible
  • No initial damage to the renal parenchyma
  • Prolonged deficiency can lead to ischemia and acute tubular necrosis
  • The renal tubules and loop of Henle are most affected by ischemia

Phases of Pre-renal ARF:

  • Extension phase: Swelling occurs,
... Continue reading "Acute Renal Failure: Signs, Classification, and Diagnosis" »

Vertebrate Animals: Mammals, Birds, and Reptiles

Classified in Biology

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Mammals

  • Females have breasts that produce milk to feed their young.
  • The body is covered with hair.
  • Body temperature is constant.
  • Young are born alive.
  • Examples: Prototherians (e.g., the platypus), marsupials (e.g., kangaroos), and eutherians (e.g., insectivores, bats, primates, cetaceans, carnivores, Perissodactyla, and Artiodactyla).
  • Temperature: Mammals maintain a constant body temperature, typically between 38 and 40 degrees Celsius, regardless of whether they live in hot or cold climates.
  • Reproduction: Mammals reproduce viviparously with internal fertilization. They lay eggs without nutrient reserves, which are implanted and developed in the womb. The placenta provides nourishment and oxygen to the developing fetus and facilitates the excretion
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How Your Body Breathes and Uses Energy

Classified in Biology

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Cellular Respiration Explained

Respiration is the process in which glucose and oxygen are transformed inside the cell into water, carbon dioxide, and energy.

The goal is to transform glucose and oxygen into energy.

Gases involved are oxygen, which we use, and carbon dioxide, the result.

It happens inside the cell in the mitochondria.

Defining Metabolic Rate

Metabolic rate is an average of the amount of energy that a person needs. While sleeping, we spend energy in circulation, for development, breathing, and protection. We spend energy because the body is working constantly.

Function of the Breathing System

In breathing, gases are exchanged. Oxygen goes from the air to the blood, and carbon dioxide goes from the blood to the air.

Lining of the Respiratory

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Understanding Neurons and Nervous Systems

Classified in Biology

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Neurons: The Basic Unit of the Nervous System

A neuron is the basic unit in the nervous system. It is a specialized conductor cell that receives and transmits electrochemical nerve impulses. A typical neuron has a cell body and long arms that conduct impulses from one body part to another.

Three Different Parts of the Neuron:

  • The cell body
  • Dendrites
  • Axon

Types of Neurons

  • Multipolar neurons have one axon and several dendrites. These are common in the brain and spinal cord.
  • Bipolar neurons have one axon and one dendrite. These are seen in the retina of the eye, the inner ear, and the olfactory (smell) area.
  • Unipolar neurons have one process extending from the cell body. The one process divides with one part acting as an axon and the other part functioning
... Continue reading "Understanding Neurons and Nervous Systems" »