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Essential Biological Definitions: Blood, Systems, and Pathology

Blood Components and Characteristics

Chordae Tendineae: "Heart Strings"

These are fibrous cords that connect the papillary muscles to the cusps of the atrioventricular valves (mitral and tricuspid valves) in the heart.

Erythrocytes (Red Blood Cells)

The primary function of erythrocytes is oxygen transport.

Leukocytes (White Blood Cells)

Leukocytes are crucial components of the immune system, defending the body against infection and disease.

Granulocytes

Their cytoskeleton contains visible granules.

Agranulocytes

The cytoskeleton lacks granules. There are two main kinds:

• Lymphocytes: Possess large spherical nuclei.
  • T Lymphocytes: Found primarily in the lymph; they attack tumor cells.
  • B Lymphocytes:

Components of the Alpha-Ketoglutarate Dehydrogenase Reaction

1. CoA (Coenzyme A)
2. NAD⁺
3. α-Ketoglutarate Dehydrogenase Complex
4. NADH + H⁺
5. CO₂
6. α-Ketoglutarate
7. Succinyl CoA

Identifying the Reaction

The following components are involved in the reaction catalyzed by Citrate Synthase:

1. Oxaloacetate
2. Citrate
3. Acetyl CoA
4. Citrate Synthase (Enzyme)

The Acetyl Radical of Acetyl-CoA

What is the role of the acetyl radical of Acetyl-CoA?

The Role of Acetyl CoA in the Krebs Cycle

Acetyl CoA is essential for the Krebs cycle (Tricarboxylic Acid Cycle) to occur. It reacts with Oxaloacetate to start the cycle.

During the cycle, 2 CO₂ and 3 NADH + H⁺ are produced (per Acetyl CoA molecule entering the cycle). Specifically, the production of NADH and CO₂ occurs:

• 1 CO₂ and 1 NADH + H⁺ are

Which Nerve Slows the Heart Down?

The Vagus Nerve

Function of Heart Valves

Heart valves ensure one-way blood flow.

Atrioventricular Valves

• Tricuspid valve (3 cusps): Located between the right atrium and right ventricle.
• Bicuspid (mitral) valve (2 cusps): Located between the left atrium and left ventricle.
• Chordae Tendineae: Also known as 'heart strings'.

Semilunar Valves

• Pulmonary semilunar valve: Directs blood from the right ventricle to the pulmonary trunk.
• Aortic semilunar valve: Directs blood from the left ventricle to the aorta.

Arteries vs. Veins

Arteries carry oxygenated blood away from the heart to the body, while veins carry oxygen-poor blood back from the body to the heart.

Three Functions of Blood

Blood has three main functions:

1. Transportation:

1. Human Beings and Health

The World Health Organization (WHO) defines health as 'the complete physical, mental and social well-being, not only the absence of disease'.

The Environment

Healthy surroundings should be free of biological, physical or chemical elements that are harmful to your health.

Personal Characteristics

Genetic factors, age and gender predispose people to suffer from certain types of illnesses.

Lifestyle

Healthy habits and lifestyles are very important for staying healthy.

Healthcare

It is essential to have an efficient healthcare system to guarantee public health.

Vital Signs

Vital signs are physiological parameters that inform us of our state of health or the evolution.

Cause -> Organic Alteration -> Symptoms and Signs ->

Nutrients and Life Stages

The quantity of nutrients that our body needs depends on the stage of life we are in.

• Breastfeeding (0–6 months): Requires breast milk.
• Childhood: Diet gradually becomes similar to an adult diet. Children generally require more calories for growth.
• Adolescence: Nutritional needs are similar to adults.

Nutritional Needs During Adulthood

Specific needs apply, especially during pregnancy. Pregnant women require approximately 300 kcal more per day, increased proteins, specific vitamins (e.g., folic acid), minerals (e.g., calcium), water, and fiber.

Nutritional Needs in Old Age

Older adults generally require similar nutrients to adults, but fewer calories overall.

Macronutrient Distribution and Calories

Recommended Daily Allowance... Continue reading "Essential Health Metrics: Nutrition, Diagnosis, and Disease Facts" »

Continental Drift

Pangaea

Plankton

Holoplankton

Zooplankton

Meroplankton

Shark Anatomy and Physiology

Spiracles

Swim Bladder

Lateral Line

Cartilage

Operculum

Marine Reptiles

Crocodile Mothering

Marine Reptile Features

Non-specific defenses

act against any type of microorganism or foreign particle. This action is carried out by phagocytes: white blood cells that trap and eliminate pathogenic microorganisms. This process is called phagocytosis.

INFLAMMATORY RESPONSE

is a non-specific defense mechanism. When pathogens get through the external barriers, the blood cells dilate to increase the blood flow. The result is pus.

Specific defenses

act against specific microorganisms or foreign molecules. Other types of leukocytes, called lymphocytes, produce proteins called antibodies. Antibodies are specific for each microorganism and destroy or inactivate the invading agents.

INCUBATION - this is the time between the moment the pathogenic agents invade organisms and the... Continue reading "Understanding Body Defenses and Diseases: A Comprehensive Guide" »