Mutations, Evolution, and Genetics
Classified in Biology
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Types of Mutations
Point Mutations
A change in a single nucleotide.
- Substitution: One nucleotide is incorrectly added in place of the correct complementary nucleotide.
- Insertion: One or more extra nucleotides are added to the growing DNA strand; this can lead to a frameshift.
- Deletion: One or more nucleotides are eliminated from the growing DNA strand; this can lead to a frameshift.
Chromosome Mutations
Changes in the structure or number of chromosomes.
Structural Mutations
These are due to two simultaneous breakages in nuclear chromosomes. This can cause:
- Deletion: The loss of a chromosomal segment.
- Duplication: A region of the chromosome is repeated.
- Inversion: The change in direction of the chromosomal segment.
- Translocation: A segment splits off from