Key Genetics and Cell Division Terminology Explained

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Glossary of Genetics and Cell Biology Terms

Basic Genetic Concepts

Allele
A variant form of a gene.
Chromosomes
Threadlike structures made of DNA molecules that contain the genes.
DNA (Deoxyribonucleic acid)
A complex molecule containing the genetic information that makes up the chromosomes.
Gene
A segment of DNA on a chromosome that codes for a specific trait.
Genotype
The genetic constitution of an individual organism.
Phenotype
The set of observable characteristics of an individual resulting from the interaction of its genotype with the environment.
Trait
A specific characteristic of an organism.

Cell Division and Reproduction

Cell Reproduction
The process by which cells produce new cells. In many cases, this involves creating exact copies of the cells they replace, such as in mitosis.
Centrioles
A cell organelle that aids in cell division in animal cells only.
Diploid Cell
A cell containing two complete sets of chromosomes (2n), one from each parent.
Haploid Cell
A cell containing only one set of chromosomes (n).
Meiosis
A type of cell division that results in four daughter cells each with half the number of chromosomes of the parent cell, as in the production of gametes.
Phases of Meiosis
The process occurs in two main stages, Meiosis I and Meiosis II:
  1. Prophase I, Metaphase I, Anaphase I, Telophase I
  2. Prophase II, Metaphase II, Anaphase II, Telophase II
Mitosis
A type of cell division that results in two daughter cells each having the same number and kind of chromosomes as the parent nucleus, typical of ordinary tissue growth.
Phases of Mitosis
The process occurs in four main phases:
  1. Prophase
  2. Metaphase
  3. Anaphase
  4. Telophase
Sexual Reproduction
A reproductive process that involves two parents who combine their genetic material to produce a new organism, which differs from both parents.

Mendelian Genetics and Crosses

Dihybrid Cross
A cross between two individuals that differ in two observed traits.
Dominant Allele
An allele whose trait always shows up in the organism when the allele is present.
F1 Generation
The first filial generation, which is the offspring of the P generation.
F2 Generation
The second filial generation, which is the result of a cross between two F1 individuals.
Heterozygous
Having two different alleles for a particular gene.
Homozygous
Having two identical alleles for a particular gene.
Law of Independent Assortment
The principle stating that genes for different traits can segregate independently during the formation of gametes.
Law of Segregation
The principle stating that during the production of gametes, the two copies of each hereditary factor segregate so that offspring acquire one factor from each parent.
Monohybrid Cross
A mating between two individuals with different alleles for one trait.
Parental Generation (P Generation)
The adults used in the first experimental cross of a breeding experiment.
Punnett Square
A diagram used to predict the genotypes of a particular cross or breeding experiment.
Recessive Allele
An allele that is masked when a dominant allele is present.
Test Cross
A genetic cross between a homozygous recessive individual and a corresponding suspected heterozygote to determine the genotype of the latter.

Molecular Genetics

Protein
A complex macromolecule composed of one or more long chains of amino acids.
Transcription
The process by which the DNA sequence of a gene is copied into a complementary RNA molecule (mRNA).
Translation
The process by which genetic information coded in messenger RNA (mRNA) directs the formation of a specific protein at a ribosome.

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