Cell Biology Fundamentals: Structure, Function, and Division

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Cell Theory Fundamentals

  1. All living things are composed of one or more cells.
  2. The cell is the basic unit of life.
  3. All cells originate from pre-existing cells.

Types of Cells

Prokaryotic Cells
Simple structure, lack a nucleus, and contain no membrane-bound organelles (e.g., bacteria).
Eukaryotic Cells
Complex structure, possess a nucleus and various organelles (e.g., plant and animal cells).

Cell Organelles: Structure and Function

Organelles Common to Plant and Animal Cells

Cell Membrane
Controls the entry and exit of substances.
Cytoplasm
Jelly-like substance that holds organelles; site of many cellular reactions.
Nucleus
Controls cell activities and holds the cell's DNA.
Nucleolus
Responsible for making ribosomes.
Ribosomes
Sites of protein synthesis (make proteins).
Mitochondria
Generates ATP (energy) through cellular respiration.
Rough Endoplasmic Reticulum (Rough ER)
Transports proteins.
Smooth Endoplasmic Reticulum (Smooth ER)
Synthesizes fats and lipids.
Golgi Apparatus
Packages and ships proteins and lipids.
Vesicles
Small sacs that transport materials within the cell.
Vacuoles
Storage for water and waste (typically small in animal cells).
Lysosomes
Contain enzymes to digest waste and cellular debris (more common in animal cells).

Organelles Unique to Plant Cells

Cell Wall
Provides structural support and protection.
Chloroplasts
Site of photosynthesis.
Large Central Vacuole
Stores water and helps maintain turgor pressure.

Organelles Unique to Animal Cells

  • Centrioles: Assist in cell division.
  • Higher quantity of lysosomes.

Cell Labeling Requirements

Key structures required for labeling diagrams:

Animal Cell Labels

  • Membrane, Cytoplasm, Nucleus, Nucleolus, Ribosomes, Mitochondria, ER (Smooth/Rough), Golgi Apparatus, Small Vacuoles, Lysosomes, Centrioles.

Plant Cell Labels

  • All structures listed for animal cells, plus: Cell Wall, Chloroplasts, and Large Central Vacuole.

Reasons for Cell Division

  1. Growth
  2. Repair of damaged tissue
  3. Reproduction (Asexual or Sexual)

Types of Cellular Reproduction

Asexual Reproduction
Involves one parent, producing genetically identical offspring (e.g., mitosis, budding, binary fission).
Sexual Reproduction
Involves two parents, resulting in genetically unique offspring.

Osmosis Versus Diffusion

Diffusion
The movement of particles from an area of high concentration to an area of low concentration.
Osmosis
The movement of water across a semipermeable membrane toward the area of higher solute concentration.

The Cell Cycle Stages

Interphase
The cell grows, DNA replicates, and the cell prepares for division.
Mitosis
The nucleus divides (Prophase, Metaphase, Anaphase, Telophase).
Cytokinesis
The cytoplasm splits, resulting in two identical daughter cells.

Mitosis Phases (PMAT)

  • Prophase: Chromosomes condense, the nucleus disappears, and the spindle fibers begin to form.
  • Metaphase: Chromosomes align along the center (metaphase plate) of the cell.
  • Anaphase: Chromatids pull apart and move toward opposite poles.
  • Telophase: New nuclei reform around the separated chromosomes, and the chromosomes unwind.

Cancer Biology

Definition
Uncontrolled and abnormal cell division.
Causes
Exposure to carcinogens (e.g., UV radiation, smoking, chemicals), genetic predisposition, and certain viruses.
Tumors
  • Benign: Non-cancerous, localized growth.
  • Malignant: Cancerous, capable of invasion.
MetastasisThe process where cancer cells spread from the primary site to new areas of the body. Treatment OptionsSurgery, chemotherapy, radiation therapy, and immunotherapy.

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