Bacterial Basics: Gram Staining, Morphology, and Reproduction
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Gram Staining: Positive and Negative Bacteria
In bacteria, the cell wall is a determinant of cell shape and has also served as a classification criterion. In 1884, French bacteriologist Christian Gram developed a method to observe bacteria under light microscopy using specific staining. However, not all bacteria are stained with this method, which led to their classification into two groups: Gram-positive bacteria, which retain the stain, and Gram-negative bacteria, which do not retain the stain.
This distinction reflects structural differences in the bacterial cell wall. In Gram-positive bacteria, the wall is mainly composed of peptidoglycan and teichoic acid. In contrast, Gram-negative bacteria have, in addition to peptidoglycan, an outer membrane... Continue reading "Bacterial Basics: Gram Staining, Morphology, and Reproduction" »