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Cell Biology: Actin, Myosin, and Microtubules

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Polymerization –plus and minus ends of actin, Kd, critical concentration, phases of growth of polymers (lag, growth, and steady-state), nucleating factors, why growth occurs preferentially at plus end.

a.High Kd and Cc= ADP + Factin lower affinity actin so dissociate

b.Lower kd and Cc= Gactin/Factin + ATP higher affinity actin so dissociate

c.Profilin and thymosin: Profilin binds to (-) end = plus end grow fast

d.Thymosin buffer + actin monomer = prevent polymerization or ATP hydrolysis.

e.Actin monomer (is above Kd) & regulates actin filament assembly.

Arp2/3 comples to make a seed (nucleate) acting growth. Can create tree-like web

Myosin II structure: motor protein makes force in skeletal contraction muscles.

a.Heavy chain with NT head (ATPase... Continue reading "Cell Biology: Actin, Myosin, and Microtubules" »

Air law

Classified in Biology

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A Minimal pair is a pair of words that vary by only A single sound, usually meaning sounds that may confuse English learners, like The /f/ and /v/ infanandvan, Or the /e/ and /ɪ/ indeskanddisk

Minimal Pairs /ɪ/ and /i:/sit Seat

Minimal Pairs /e/ and /ɪ/desk disk

Minimal Pairs /e/ and /eɪ/wet wait

Minimal Pairs /æ/ and /ʌ/bat but

Minimal Pairs /əʊ/ and /ɔ:/sosaw

Minimal Pairs /ɒ/ and /əʊ/not note

Minimal Pairs /æ/ and /e/bad bed

Minimal Pairs /ɑ:/ and /ɜ:/fast first

Consonant Sounds

Minimal Pairs /b/ and /v/berryvery

Minimal Pairs /b/ and /p/buypie

Minimal Pairs /n/ and /ŋ/thinthing

Minimal Pairs /l/ and /r/alive arrive

Minimal Pairs /ʧ/ and /t/catchcat

Minimal Pairs /s/ and /ʃ/seashe

Minimal Pairs /f/ and /v/fanvan

Minimal Pairs /f/ and /h/

... Continue reading "Air law" »

The Importance of a Balanced Diet and Food Safety

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Eatwell Plate

A balanced diet:

  • Provides energy to survive.

  • Growth and repair of body tissue.

  • Bodily function.

  • Stopping us feeling hungry

  • Health and wellbeing.

5 food groups:11

  • Fruit and vegetables.

  • Starches

  • Proteins 

  • Dairy products

  • Fats and oils

The Eatwell Guide applies to everyone regardless of weight, dietary restrictions or ethnic origin.

It doesn’t apply to children under 2 years because they’ve different nutritional needs. 

Fruit and vegetables

  • Fruit and vegetables → ⅓ of food that we eat each day.

  • Eat at least 5 portions of fruit and vegetables.

  • Choose → fresh, frozen, canned, dried or juiced.

Potatoes, bread, rice, pasta and other starchy carbohydrates

  • Starchy food → ⅓ of food we eat per day.

  • Choose → higher-fibre, whole grain → contains

... Continue reading "The Importance of a Balanced Diet and Food Safety" »

Developmental Biology and Genetic Disorders

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Cellular Development Stages

The early stages of development occur at the cellular, tissue, and organ levels of organization. At the cellular level, development includes cleavage, resulting in a multicellular embryo and the formation of a blastula.

Cleavage, which encompasses DNA replication and mitotic stages, is cell division without growth and results in a morula, a ball of cells. The next cellular stage is the formation of a blastula, a hollow ball of cells with a fluid-filled cavity called a blastocoel. The blastocoel forms when the cells of the morula pump Na+ into extracellular spaces, and water follows by osmosis.

Tissue Development Stages

The tissue stages of development are the early gastrula and the neurula. The early gastrula stage begins... Continue reading "Developmental Biology and Genetic Disorders" »

The Respiratory System: Oxygen In, Carbon Dioxide Out

Classified in Biology

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Enables oxygen in the air to enter the body, expelling carbon dioxide.

1) Respiratory Tract:

Passages through which oxygen enters the lungs and carbon dioxide is expelled.

  • Nasal Passages: Air enters the nose and continues through these passages, where it is moistened and warmed. Dust and microorganisms in the air are retained here.
  • Pharynx: Air from the nasal passages reaches the pharynx, which is part of both systems.
  • Larynx: Made of cartilage. The vocal cords vibrate and enable humans to make sounds.
  • Trachea: C-shaped cartilage rings through which air travels from the larynx to the bronchi.
  • Bronchi and Bronchioles: Bronchi are two tubes that branch out from the trachea into each lung. They divide into small tubes called bronchioles, rounded sacs
... Continue reading "The Respiratory System: Oxygen In, Carbon Dioxide Out" »

Genetics: Transcription, Translation, and Genetic Code Principles

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True or False Statements:

a) Transcription and translation occur in the nucleus.

TF

b) During transcription, an RNA molecule is formed.

TF

c) Each RNA molecule can carry any amino acid.

TF

Characteristics of the Genetic Code

  • Universality: The specificity of the genetic code has been conserved from very early stages of evolution.
  • Degenerate: A particular codon always codes for the same amino acid.
  • Specificity: Each codon corresponds to a single amino acid.
  • Nonoverlapping and Commaless: The code is read from a fixed starting point as a continuous sequence of bases, taken 3 at a time.

Amino Acid Calculation:

The shortest gene discovered in human chromosome 19 consists of 1000 nucleotides, 666 nucleotides of which are introns. What is the maximum number of... Continue reading "Genetics: Transcription, Translation, and Genetic Code Principles" »

Cell Membrane Dynamics and Transport Mechanisms

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Cell Membrane Dynamics

Plasma membrane phospholipids are labeled with a fluorescent tag and then the phospholipids in one area are bleached with a laser beam to eliminate the fluorescent signal. What would one observe after the cell is incubated for a few minutes? The bleached molecules would diffuse laterally through the membrane and intermix with unbleached molecules. Cellular membranes are mosaic and fluid. Glycosylated proteins and lipids within the plasma membrane are important for cell recognition and protection.

Passive Diffusion

Passive diffusion is a spontaneous process. Water diffuses through certain organs such as the kidneys and bladder much faster than would occur by passive diffusion through a lipid bilayer alone. What accounts for... Continue reading "Cell Membrane Dynamics and Transport Mechanisms" »

Human and Plant Biology: Homeostasis, Thermoregulation, Blood Sugar, and Tropisms

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Still the Eye

Cornea Lens: More spherical lens with shorter focal length
Thinner lens with longer focal length (requires less refraction)
Suspensory Ligaments: Distant = flat; Near = round/thick

Homeostasis

Homeostasis: Maintenance of a constant internal environment despite changes in surroundings.
Control Center: The hypothalamus in the brain decides on the appropriate response. Receptors: In the skin and brain, detect changes in the body. Effectors: E.g., sweat glands, body hair, and thyroid glands change to increase/decrease body temperature.

Thermoregulation

Thermoregulation: If the body is too cold or hot, body temperature is adjusted to what it should be (negative feedback mechanism). It involves receptors linked to the hypothalamus, which
... Continue reading "Human and Plant Biology: Homeostasis, Thermoregulation, Blood Sugar, and Tropisms" »

Zika Virus: Transmission, Symptoms, and Prevention

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Zika is a mosquito-borne disease transmitted by the same mosquito that carries the dengue virus. There have also been cases of transmission through sexual intercourse.

Transmission

Most people get Zika from a mosquito bite. Mosquitoes become infected when they feed on the blood of a person already infected with the virus, and when they bite others, they can transmit the virus. Other forms of transmission include:

  • A pregnant woman can pass the Zika virus to her fetus during pregnancy or at the time of birth.
  • Zika can also be transmitted through sexual intercourse and blood transfusion.

Symptoms

Zika can cause incomplete brain development in fetuses. Common symptoms include fever, rash, joint pain, and conjunctivitis.

Prevention

To reduce the risk of

... Continue reading "Zika Virus: Transmission, Symptoms, and Prevention" »

Woman called Donna Truhana

Classified in Biology

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SPERMATOZOA 

Spermatozoa, or male gametes, are small, mothie cells (capable of movement). They carry the hereditary information from the father.
-The head, which contains the cell nucleus with the hereditary material
-A mid-piece, the many mitochondria of which generate the enrgy required for movement.
-The tail, which is called flagellum, enables them to move.
THE FORMATION OF SPERMATOZOA
The formation of spermatozoa, takes place in the seminiferous tubules, which include the interstitial cells that segretate testosterone. The walls of these tubules contain cells called germ cells, which are constantly multiplying themselves. As they multiply, the cells move towards the end of the tube and gradually mature until they become spermatozoa. The process
... Continue reading "Woman called Donna Truhana" »