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Understanding Class 1 and Class 2 Malocclusions

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Class 1 Malocclusion: Issues and Variations

Crossbite Complications

Crossbite (failure of dental arches to occlude correctly in the lateral dimension) can manifest in several ways within Class 1 malocclusion (normocclusion, often with a good relationship between the osseous bases):

  • Unilateral Crossbite: Affects one side, from the canine to the last molar.
  • Bilateral Crossbite: Affects both sides, from canine to molar. Often associated with maxillary micrognathia (narrow upper jaw) relative to the mandible. May be linked to habits like mouth breathing and finger sucking.
  • Dental Crossbite: Normocclusion with a good skeletal base relationship, but involves incorrect inclination of a specific molar or canine due to lack of space, resulting in palatal
... Continue reading "Understanding Class 1 and Class 2 Malocclusions" »

Cellular Organelles: Functions and Structures

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Organelles

An organelle is a small, specialized structure within a cell that performs a specific function. Examples include mitochondria and lysosomes.

Functions of the Cell or Plasma Membrane

  1. This structure surrounds the cell, separating it from the external environment.
  2. It forms a barrier that allows the cell to incorporate water and nutrients and remove metabolic waste.

Ribosomes

Ribosomes are organelles formed by the combination of different proteins and RNA (ribonucleic acid).

The Golgi apparatus is an organelle that receives immature proteins from the rough endoplasmic reticulum (RER) and releases vesicles containing mature proteins.

  • RE: Endoplasmic reticulum
  • PER: Ribosomes that have completed the synthesis of a protein

Location and Structure of

... Continue reading "Cellular Organelles: Functions and Structures" »

Understanding Chromosome Structure: Chromatids, Centromeres, and Kinetochores

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Chromosome Structure: A Detailed Explanation

A chromosome consists of two parallel, elongated, rod-shaped subunits called chromatids. The chromatids are not equally thick throughout their length because they contain chromomeres, which are condensed fragments of chromatin.

Chromomere size varies, but the thickness of the chromatid is roughly constant, between 0.25 and 2 micrometers.

Primary Constriction (Centromere)

A structure called the primary constriction, or centromere, divides the chromatid into two arms, which may be of equal or different lengths. This distinction allows for chromosome classification:

  • Metacentric chromosome: Central centromere and arms of equal length.
  • Submetacentric chromosome: Centromere shifted upward, resulting in upper
... Continue reading "Understanding Chromosome Structure: Chromatids, Centromeres, and Kinetochores" »

Understanding Diseases: Types, Risks, and Prevention

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Defining Health and Disease

Health is typically defined as the state where the body's organs and systems are functioning correctly. When an alteration occurs in one or more of these systems, disrupting their function, a disorder known as disease arises. A disease manifests through a series of bodily changes or abnormalities called symptoms.

Classifying Disease Types

Diseases can be categorized based on their causes:

  • Infectious Diseases: Caused by microorganisms such as viruses, some bacteria, fungi, and protozoa.
  • Environmental Diseases: Resulting from components of the physical environment, such as extreme heat or cold, air pollution, radiation, etc.
  • Toxic Diseases: Originating from breathing or ingesting certain toxic substances, like carbon monoxide
... Continue reading "Understanding Diseases: Types, Risks, and Prevention" »

Ecosystems: Concepts, Function, and Types

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Fundamental Ecological Concepts

Key Ecological Definitions

  • Biosphere: The set of all creatures that inhabit the Earth.
  • Microorganisms: Bacteria or protozoa.
  • Ecosystem: All living beings that inhabit a particular place, interacting with their environment.
  • The Ecosphere: The set of all ecosystems on our planet.
  • Ecosystems: Composed of biocoenosis and biotope.
  • Biocoenosis: The living community within an ecosystem.
  • Biotope: The inorganic part of an ecosystem.
  • Habitat: The physical location within an ecosystem where individuals of a particular species live.
  • Ecological Niche: The role of a species in the ecosystem. It is defined by behavior, the type of food consumed, where food is sought, etc.

Abiotic Factors in Ecosystems

These are the non-living components... Continue reading "Ecosystems: Concepts, Function, and Types" »

Endosymbiotic Theory and Cell Structure: Prokaryotic vs. Eukaryotic

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The Endosymbiotic Theory

The endosymbiotic theory, proposed by Lynn Margulis in 1967, suggests that eukaryotic cells originated from a primitive cell engulfing other prokaryotic cells, establishing an endosymbiotic relationship. This theory explains the origin of mitochondria and chloroplasts, which resemble bacteria in size and reproduce by division. Crucially, both possess their own DNA and ribosomes, similar to prokaryotes. The acquisition of these bacterial precursors provided eukaryotic cells with aerobic respiration (mitochondria) and photosynthetic capabilities (chloroplasts). This symbiosis offered the prokaryotes a secure environment and food, while their DNA became partially incorporated into the host cell's DNA.

Origin of Eukaryotic

... Continue reading "Endosymbiotic Theory and Cell Structure: Prokaryotic vs. Eukaryotic" »

Antidepressants and Antiepileptic Medications

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Antidepressants

Tricyclic Antidepressants (TCAs) have a core of condensed 3-rings, a side chain, and amine ends. The introduction of oxygen and nitrogen in the core and the branched side chain are associated with antidepressant action, and the introduction of halogens increases this action. These drugs are well absorbed orally but have low bioavailability. They can also be administered intramuscularly. They tend to bind to plasma proteins and are easily metabolized. TCAs are typically administered twice a day.

Adverse Reactions:

  • Cardiovascular: Hypotension, palpitations, tachycardia.
  • Anticholinergic: Dry mouth, constipation, urinary retention, nasal congestion, blurred vision (glaucoma).
  • Neurological: Confusion, hallucinations, tremors of the hand
... Continue reading "Antidepressants and Antiepileptic Medications" »

Overview of the Nervous System Development

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Overview of the Nervous System

Cervical Plexus

Supplies the skin of the neck and a deep one that supplies most of the muscles of the neck and the diaphragm muscle.

Brachial Plexus

Three primary trunks:

  • 1st primary trunk: C5-C6
  • 2nd primary trunk: C7
  • 3rd primary trunk: C8-T1

Three secondary trunks:

  • External anterior trunk
  • Internal anterior trunk
  • Posterior trunk

Lumbar Plexus

Gives side branches to the psoas muscle.

Terminal branches:

  • Obturator nerve, which serves the thigh.
  • Femoral nerve, which extends the knee (quadriceps).

The innervation of this plexus territory does not pass the knee.

Sacral Plexus

Gives collateral branches to the muscles of the hip.

Delivers a single terminal branch, the thickest nerve, called the sciatic nerve.

Innervates the hamstrings and... Continue reading "Overview of the Nervous System Development" »

Nervous System Anatomy: Somatic, Central, and Spinal Components

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Nervous System Anatomy

The nervous system is a complex network responsible for coordinating actions and transmitting signals throughout the body. It can be broadly divided into several key components:

Somatic Nervous System

The Somatic Nervous System is composed of mixed nerves, containing both sensory and motor axons. These nerves innervate somatic effectors, primarily skeletal muscles.

Central Nervous System (CNS)

The Central Nervous System has a sensory or afferent division that brings information from sensory receptors in the periphery. This includes visual, auditory, somatosensory, and chemoreceptor information. This information is transmitted to higher levels, reaching the motor cortex. The motor or efferent division carries information towards... Continue reading "Nervous System Anatomy: Somatic, Central, and Spinal Components" »

Photosynthesis: C3, C4, and CAM Pathways, Pigments, and Factors

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Plant Photosynthesis: C3, C4, and CAM Pathways

C4 Plants

C4 metabolism has a higher energy cost than C3, requiring 5 ATP and 2 NADPH per CO2 fixed. C4 plants are adapted to tropical, subtropical, relatively dry environments with bright illumination and can withstand high and low relative humidity. They fix CO2 using PEP carboxylase and then pump it to the bundle sheath cells.

C3 Plants

C3 plants use 3 ATP and 2 NADPH and are adapted to temperate climates with moderate temperatures and high relative humidity.

Exogenous Factors Affecting Photosynthesis

  • Light
  • Concentration of CO2 and O2
  • Temperature
  • Availability of water and nutrients

Endogenous Factors Affecting Photosynthesis

Type of plant (C3, C4, or CAM), stomatal density, leaf area, leaf age, hormone... Continue reading "Photosynthesis: C3, C4, and CAM Pathways, Pigments, and Factors" »