Notes, summaries, assignments, exams, and problems for Biology

Factors Influencing Drug Absorption

A) Factors Related to the Drug

a) Drug Properties

• Degree of Ionization: Highly ionized drugs are poorly absorbed.
• Lipid Solubility: High lipid-water partition coefficients increase absorption.
• Valency: Ferrous salts are absorbed more than ferric; Vitamin C increases iron absorption.
• Molecular Weight (MW): Low MW drugs have a faster rate of absorption; high MW drugs have a slower rate. Adding procaine to penicillin increases MW, decreases the rate of absorption, and prolongs action.

b) Pharmaceutical Form

Solutions are absorbed better than suspensions or tablets.

B) Factors Related to the Patient

• Route of Administration: Absorption from mucous membranes is very rapid from alveolar mucosa, less from sublingual, small

List the Most Important Functions of Blood

• Heating: transporting or regulating body heat
• Transport nutrients and O2 to the cell
• Defense mechanism against pathogens
• Transport CO2 waste from cells
• Transport of hormones: insulin

Why the Circulatory System is Vital

• Because it keeps the cells provided with what they need and removes what they need to get rid of.
• By blood is the means by which some organs influence other organs to perform functions (HORMONES)

Identify the Main Types of Blood Vessels

Observe the Blood Components

A. CENTRIFUGATION...

PLASMA... Continue reading "Understanding the Circulatory System: Functions and Types" »

Cell Structure and Function

Cell Membrane

The cell membrane is a dynamic structure known as the fluid mosaic model, consisting of:

• Phospholipid Bilayer: Forms the basic structural framework.
• Proteins: Integral proteins (embedded in the membrane) and peripheral proteins (attached to the membrane surface).
• Cholesterol: Provides stability and regulates fluidity.
• Carbohydrates: Often attached to proteins (glycoproteins) or lipids (glycolipids) for cell recognition.

Energy Flow and Metabolism

• Energy Flow: From sunlight to producers (photosynthesis) and then through consumers (cellular respiration).
• Matter Cycling: Carbon, nitrogen, and other elements cycle through living organisms and the environment.
• Metabolism Types: Anabolism (building molecules) and Catabolism

Osmosis and Passive Transport

Osmosis is the movement of particles from a high concentration to a low concentration. Specifically, it is the movement of a solvent, such as distilled water, through a semipermeable membrane. This process occurs when two solutions with different concentrations of solutes are present in the same recipient.

Mitosis: Somatic Cell Division

Mitosis creates identical cells through cell division. This process is essential for growth and produces body cells, also known as somatic cells.

Phases of Mitosis

• Prophase: Chromosomes become visible and begin condensing.
• Metaphase: The nuclear membrane breaks down, and the chromosomes line up in the middle of the cell.
• Anaphase: The chromatids separate and move toward opposite sides

Tissue

Tissue: is formed of cells of a similar type that work together to carry out specific functions. Most tissue cells are held together by their own intercellular substances. The human body has four different tissue groups:

Connective Tissue

Connective tissue proper: It surrounds and connects organs and has a gel-like intercellular matrix. Ex: Tendons and ligaments.

Adipose tissue: Stores lipids for protection and energy reserves, using cells called adipocytes.

Cartilaginous tissue: It has a solid, elastic intercellular matrix and cells known as chondrocytes.

Bone tissue: Its rigidity allows it to support the body, along with cartilage.

Blood tissue: It is responsible for the transport of nutrients, hormones and waste, as well as for protecting... Continue reading "Human Tissues, Organs and Body Systems" »

Key Terms in Genetics

DNA: deoxyribonucleic acid, substance that carries genetic information in a cell.

Protein: organic compound that consists of long chains of molecules and is an essential part of living things.

Genetic code: set of instructions in a gene that tells a cell how to make a specific protein.

Genome: set of genes in an organism.

Genetic engineering: manipulation of genetic material to change the traits of an organism.

Biotechnology: biological techniques to create improved products for human consumption.

Genes and Their Role

Genes: are located in the chromosomes and are the basic unit of inheritance that carry genetic information. Genes consist of DNA, the molecule that gives cells and all organisms biological information.

Cell Cycle

Pharyngeal Arches

• First Arch: Mandibular nerve, Meckel's cartilage, muscles of mastication, tensor tympani, mylohyoid, anterior belly of the digastric
• Second Arch: Facial nerve, Reichert's cartilage (hyoid bone), muscles of facial expression, posterior belly of the digastric, stylohyoid, stapedius
• Third Arch: Glossopharyngeal nerve, hyoid bone, stylopharyngeus muscle
• Fourth Arch: Vagus nerve, laryngeal cartilages, soft palate muscles (except tensor veli palatini), pharyngeal muscles (except stylopharyngeus)
• Fifth Arch: Vagus nerve, no specific structure, arytenoid muscle
• Sixth Arch: Vagus nerve (recurrent laryngeal), no specific structure, intrinsic muscles of the larynx (except cricothyroid and arytenoid)

Pharyngeal Pouches

• First Pouch: Auditory tube

Microorganisms: Definitions and Characteristics

Place the correct number in the boxes to match the organism with its definition.

1. Fungus: A spore-producing organism that absorbs nutrients from the environment.
2. Protist: Any eukaryotic organism that is not an animal, plant, or fungus.
3. Bacteria: A prokaryotic organism with peptidoglycan in its cell walls.
4. Archaea: A prokaryotic organism without peptidoglycan in its cell walls.
5. Virus: A microscopic particle that cannot replicate on its own.

Understanding Hosts in Biology

A host is:

• An infected protein
• A prokaryotic organism
• A living thing that a virus or parasite uses for shelter
• A cell destroyed by a virus

Extreme Habitats of Archaea

Label these extreme habitats of Archaea with the correct names from the box:... Continue reading "Microorganisms, Reproduction, and Species Classification" »

Structural Components of Viruses

• Capsid: Protein shell that encloses a viral genome; may be rod-shaped, polyhedral, or more complex in shape
• Viral envelopes: Membrane that cloaks the capsid that in turn encloses a viral genome

Obligate Intracellular Parasites

Viruses can only reproduce within host cells because they lack metabolic enzymes, ribosomes, and other equipment for making proteins.

• Identifying host cells: "Lock and key" fit between proteins on the outside of the virus and specific receptor molecules on the host's surface (which originally evolved for functions that benefit the host).

Bacterial Defenses Against Phages

While phages have the potential to wipe out a bacterial colony in just hours, bacteria have defenses against phages:

• Natural