Benign Epithelial Lesions

Squamous Cell Papilloma

Age: Mid-age
Site: Palate, uvula, cheek, lip, tongue, gingiva
Characteristics:

• Color: White to pinkish (depending on keratinization)
• Shape: Cauliflower-like
• Surface: Rough, irregular (finger-like projections)
• Texture: Firm or soft (depending on keratinization)
• Sessile or pedunculated

Histological Features:

1. Hyperplastic stratified squamous epithelium
2. Acanthosis and hyperkeratosis
3. Intact basal layer
4. Thin central branching core of connective tissue carrying nutrition

Verruca Vulgaris (Wart)

Reactive lesion, autoinoculation
Etiology: HPV 2, 4, 6
Histological Features:

1. Intranuclear inclusion bodies
2. Koilocytes
3. Cupping effect of rete ridges
4. Granular cell layer

Keratoacanthoma

True, self-limiting lesion
Age: Older males
...

Biology 105/106: Exam 1 Study Material

This document outlines key concepts for Biology 105/106 Exam 1, covering fundamental principles of science, life, cells, metabolism, and energy, along with essential lab topics.

Chapter 1: The Scientific Process

• Science as a Process:
  1. Observation: Noticing phenomena.
  2. Question: Forming a formal hypothesis.
  3. Hypothesis: A testable explanation for an observation.
  4. Experimentation: Testing the hypothesis.
  5. Data Analysis: Drawing conclusions from results.
  6. Communication: Sharing findings and restarting the process with new questions.
• Hypothesis vs. Prediction: Understand the distinction.
• Experiments:
  • Controls: Elements kept constant to ensure valid results.
  • Variables:
    • Independent Variable: The factor manipulated by the experimenter.

Female Reproductive System

Key Components and Functions

Uterus

The myometrium, the middle layer of the uterine wall, is responsible for the contractions during childbirth.

Vagina

The vagina is an elastic tube that facilitates penetration during sexual intercourse.

Vulva

The vulva, the external female genitalia, consists of the labia majora, labia minora, and the clitoris, which is responsible for sexual pleasure.

Bartholin's Glands

These glands produce lubricant to facilitate sexual intercourse.

The Ovarian Cycle

Each ovarian cycle lasts approximately 28 days and consists of three phases:

1. Follicular Phase (14 days): An egg cell matures.
2. Ovulation: The mature egg is released from the ovary into the fallopian tube.
3. Luteal Phase (14 days): The corpus luteum,

The Origin of New Species

The changes that living things experience as time passes lead to the creation of new species. In this long and complex process, there are 4 stages:

1. Production of Evolutionary Changes in Populations

This happens because natural selection favors some individuals and not others. As a consequence, the new populations are different from the original ones, although they still belong to the same species.

2. Genetic Isolation of the New Population

So that a new species can evolve, it is essential that the members of the new population do not reproduce with those of the previous population. In other words, they become independent and stop sharing genetic information with the original population.

3. Gradual Differentiation

After...

Structural Components of Viruses

• Capsid: Protein shell that encloses a viral genome; may be rod-shaped, polyhedral, or more complex in shape
• Viral envelopes: Membrane that cloaks the capsid that in turn encloses a viral genome

Obligate Intracellular Parasites

Viruses can only reproduce within host cells because they lack metabolic enzymes, ribosomes, and other equipment for making proteins.

• Identifying host cells: "Lock and key" fit between proteins on the outside of the virus and specific receptor molecules on the host's surface (which originally evolved for functions that benefit the host).

Bacterial Defenses Against Phages

While phages have the potential to wipe out a bacterial colony in just hours, bacteria have defenses against phages:

• Natural

Protein Structure:

It is a three-dimensional structure. Polypeptides are folded to produce a globular shape. The structure is stabilized by intermolecular bonds between amino acids.

Primary Structure:

Is the sequence of amino acids in the polypeptide chain. It is codified by a gene. The sequence of nucleotides in a gene codify the sequence of amino acids in a polypeptide chain.

Secondary Structure:

3-dimensional conformation. It's the formation of beta-pleated and alpha helices, established by hydrogen bonds. It's the bond formed between the carboxyl group and the amino group.

Tertiary Structure:

The polypeptide chain is folded and established by interactions between R groups. The conformation is established by intramolecular bonds and interactions...

The Cell Cycle

The cell cycle consists of two main phases: interphase and mitosis (M phase) [3].

Interphase

Interphase is further divided into three phases:

1. G1 phase (Gap 1): During this phase, the cell grows in size and carries out normal metabolic activities [4].
2. S phase (Synthesis): In this phase, DNA replication and chromosome duplication occur [4].
3. G2 phase (Gap 2): The cell continues to grow and prepares for cell division [4].

Mitosis (M phase)

Mitosis is the actual phase of cell division and is divided into four stages:

1. Prophase: Chromosomes condense, the nuclear envelope and nucleolus disappear, and spindle fibers start to appear [4].
2. Metaphase: Chromosomes align at the equatorial plate [4].
3. Anaphase: Centromeres divide, and chromatids move towards

FUNGI KINGDOM

Cellular Organization:

Unicellular or multicellular, the cells are eukaryotic, they have no tissues.

Size and Shape:

Unicellular fungi, like yeast, are round or oval and microscopic in size.

Nutrition:

Heterotrophic, many are saprophytes, feeding on organic material from animals or plants.

Lifestyle:

They can be free-living symbionts or parasites.

Reproduction:

Unicellular asexual, multicellular asexual, or sexual.

PROTOCTIST KINGDOM PROTOZOA

Cellular Organization:

Unicellular, they have no tissues.

Size and Shape:

Oval, round, oblong, half-moon. All are microscopic.

Nutrition:

Heterotrophic, feeding on bacteria and algae.

Habitat and Lifestyle:

Most are free-living.

Reproduction:

They reproduce asexually by binary fission.

Movement:

They move by using...