Understanding the Immune System and Its Defenses
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Immunology
By removing serum from pustules of the udder of a cow and injecting it into human skin, an individual suffered from a mild illness but never acquired smallpox. It was the first experiment of active immunization.
1. The Body's Defenses
All organisms have developed mechanisms of defense against the invasion of pathogens. These mechanisms may be nonspecific, preventing entry into the body or destroying them quickly, or very specific, which is known as the immune response.
1.1 Nonspecific Defense Mechanisms
These act against any organism or foreign substance. They are of three types:
a) Natural Barriers: Skin and secretions from the mucosal surfaces.
- Skin is a mechanical barrier because its outermost stratum corneum is fully keratinized.
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