Notes, summaries, assignments, exams, and problems for Biology

Joints: Definition and Classification

A joint, also known as an articulation, is the point where two or more bones meet. Joints allow for movement, flexibility, and support in the skeletal system.

Classification of Joints

Joints can be classified based on their structure and function:

Structural Classification

1. Fibrous Joints: Held together by dense connective tissue (e.g., sutures in the skull).
2. Cartilaginous Joints: Connected by cartilage (e.g., intervertebral discs, symphysis pubis).
3. Synovial Joints: Characterized by a fluid-filled space between bones (e.g., hinge joints like the elbow, ball-and-socket joints like the shoulder).

Functional Classification

1. Synarthroses: Immovable joints (e.g., sutures in the skull).
2. Amphiarthroses: Slightly movable joints

Nervous and Endocrine Systems

The nervous system receives external and internal stimuli, interprets them, and decides an appropriate response. The response is executed by the effector organ or tissue. Nervous tissue is made up of cells called neurons.

Stimulus → Nervous System → Effectors → Muscles, Glands

Neuron Structure

• Cell body: The central part of the neuron.
• Dendrites: Extensions of the cell body. They receive the nerve impulse and transmit it to the cell body.
• Axon: A long fiber extending from the cell body. It transmits the nerve impulse to other neurons or effector cells.
• Myelin sheath: This layer protects the axon and increases the speed of the nerve impulse.
• Axon terminals: These are located at the end of the axon. They contain neurotransmitters,

Essential Concepts in Muscle Physiology

Skeletal Muscle Anatomy: The Sarcomere

8. A sarcomere (The basic contractile unit)
9. Myofibril (A bundle of myofilaments)
10. T-tubule; terminal cistern (Components of the Triad)

Sarcomere Components Defined

29. Thin filaments
30. I band: (Light band containing only thin filaments; spans from the Z line into the sarcomere.)
31. Z line: (Anchors thin filaments and defines the boundary of a sarcomere.)
32. H band: (Central part of the A band where only thick filaments are present—no overlap with thin filaments.)
33. M line: (The center of the sarcomere, within the H zone, where thick filaments are linked.)

Excitation-Contraction Mechanisms

6. None of these: The correct answer is the Nicotinic ACh receptor, which was not listed.
7. Sarcoplasmic reticulum

Human Energy: The Aerobic Advantage

Humans, as members of the Animal Kingdom, primarily utilize aerobic cellular respiration for energy production. This vital process involves our cells using oxygen to efficiently break down glucose (sugar) into ATP, the fundamental energy currency our bodies require. This intricate process occurs within the mitochondria, famously known as the "powerhouse" of the cell.

Humans demand substantial energy for movement, cognitive functions, and growth, making aerobic respiration perfectly suited for our active lifestyle. Our ancestors similarly required high energy levels for hunting, long-distance travel, and complex thought, which likely explains our evolutionary reliance on this efficient method. The complete pathway,... Continue reading "Cellular Respiration: Fueling Life and Classifying Organisms" »

Cell Theory Fundamentals

1. All living things are composed of one or more cells.
2. The cell is the basic unit of life.
3. All cells originate from pre-existing cells.

Types of Cells

Prokaryotic Cells

Simple structure, lack a nucleus, and contain no membrane-bound organelles (e.g., bacteria).

Eukaryotic Cells

Complex structure, possess a nucleus and various organelles (e.g., plant and animal cells).

Cell Organelles: Structure and Function

Organelles Common to Plant and Animal Cells

Cell Membrane

Controls the entry and exit of substances.

Cytoplasm

Jelly-like substance that holds organelles; site of many cellular reactions.

Nucleus

Controls cell activities and holds the cell's DNA.

Nucleolus

Responsible for making ribosomes.

Ribosomes

Sites of protein synthesis (make proteins)

Anatomy, Pathology, and Lab Essentials

Bones: Rigid organs that make up the skeletal system of vertebrates, providing support and protection for the body’s organs.

Cranium: The part of the skull that protects the brain.

Backbone: Also known as the spine or vertebral column, a flexible and strong structure running along the center of the back, made up of small bones called vertebrae.

Skull: A bony framework enclosing the brain of a vertebrate.

Joints: The points where two or more bones, or a bone and cartilage, are attached in the body.

Ligaments: Short bands of tough, flexible fibrous connective tissues that connect two bones or cartilages, or hold joints together.

Cartilage: Firm, flexible connective tissue found in various forms, from which the... Continue reading "Anatomy, Pathology, and Lab Essentials: A Comprehensive Glossary" »

The Human Respiratory System

By Marco Rios

Ventilation: Air Movement in the Lungs

Pulmonary Ventilation

The total volume of air breathed in and out per minute.

Alveolar Ventilation

The volume of air exchanged between the atmosphere and the alveoli per minute.

The Lungs: Core Organs of Respiration

A pair of organs consisting of the lower part of the respiratory airways, pulmonary circulation, and connective tissue.

Pleural Sacs and Cavity

Thin, fluid-filled membranes that enclose the lungs. The space between the pair is known as the pleural cavity.

Alveolar Cell Types

Type I Cells

Form the walls of the alveoli, facilitating gas exchange.

Type II Cells

Secrete pulmonary surfactant.

Pulmonary Surfactant

A substance that reduces the surface tension of water inside... Continue reading "Human Respiratory System Functions" »

Carbohydrates: Structure and Classification

Classification

• Monosaccharides: Single sugar unit (e.g., glucose, fructose).
• Disaccharides: Two sugar units joined (e.g., sucrose = glucose + fructose).
• Polysaccharides: Many sugar units linked (e.g., starch, glycogen).

Aldose vs. Ketose

• Aldose: Contains an aldehyde (-CHO) group (e.g., glucose).
• Ketose: Contains a ketone (>C=O) group (e.g., fructose).
• Number of Carbons: Triose (3C), Tetrose (4C), Pentose (5C), Hexose (6C).

Structural vs. Stereoisomers

• Structural Isomers: Same molecular formula, different bonding patterns or structure.
• Stereoisomers: Same connectivity, different spatial arrangement of atoms.

Chiral Carbons

• Chiral Carbon: A carbon atom bonded to four different groups, creating an asymmetric center.

Most living things obtain their energy either directly or indirectly from the energy of sunlight captured through photosynthesis.

Photosynthesis in 2 Stages

1. Pigments in the leaves' cells (chlorophyll) capture or absorb the sun's energy, which is used to power the second stage. The leaf cells also need water (absorbed through roots) and carbon dioxide (that enters through small openings on the undersides of leaves called stomata).
2. Inside the chloroplasts, water and carbon dioxide are transformed into glucose and oxygen. Plants use glucose for food and store what they don't need as starch (energy for later use) and cellulose (that makes up the cell walls). Oxygen and water exit the leaf through the stomata.

Stomata

Carbon dioxide enters the plant... Continue reading "Photosynthesis and Cellular Respiration in Plants" »

Understanding DNA Analysis Techniques

Restriction Enzymes: Cutting DNA with Precision

Role: Restriction enzymes cut foreign DNA into pieces to prevent infection.

Mechanism: Special proteins recognize specific DNA sequences (restriction sites) and cut at those locations. Bacteria protect their own DNA from self-cleavage using methylation.

Example: EcoRI

EcoRI recognizes the sequence GAATTC and cuts between G and A. This creates "sticky ends" (overhangs) like G- and AATT, which help join DNA fragments.

DNA Fragmentation and Gel Electrophoresis

DNA is cut into fragments using restriction enzymes. These fragments are then sorted by size using gel electrophoresis.

• Shorter fragments travel farther and faster in the gel.
• DNA fragments are stained for visibility,