Notes, summaries, assignments, exams, and problems for Biology

Mendelian Principles of Inheritance

Gregor Mendel

• In the 19th century, he studied inheritance: the passing of characteristics from parents to offspring.
• His work was based on the study of the crossing of different varieties of plants.
• The species chosen was the pea (Pisum sativum).

Method

• Characteristic selection
• Obtaining pure-bred individuals for those characteristics

Parental generation (P)

• Crossing two different pure breeds to obtain descendants

First filial generation (F1)

• Crossing F1 individuals and studying their descendants

Second filial generation (F2)

Complete Inheritance

In the heterozygote, the dominant phenotype is manifested.

Special Cases in Genetics

Complete Inheritance

In the heterozygote, the dominant phenotype is manifested.

Intermediate Inheritance

The... Continue reading "Mendelian Genetics: Principles of Inheritance" »

Early Chordates and the Rise of Tetrapods

The earliest known chordate, Myllokunmingia, is found in the Chengjiang fauna. One of the major challenges for early tetrapods was supporting their bodies on land, along with reproductive and sensory adaptations. Tetrapod limbs consist of three segments: the stylopod (humerus/femur), zeugopod (ulna/radius, tibia/fibula), and autopod (wrist/fingers, ankle/toes). Tiktaalik represents a key transitional fossil between fish and tetrapods.

Amphibians and Amniotes

Amphibians, with over 4,000 living species, represent a halfway point in the transition to land. They still rely on water for breeding and maintaining water balance. Amniotes, including reptiles, birds, and mammals, evolved a semipermeable shell made... Continue reading "Evolution of Life: From Early Chordates to Modern Biodiversity" »

The Human Heart: Structure and Function

The heart is a muscular organ situated between the lungs, slightly to the left. Its walls, known as the myocardium, are responsible for pumping blood.

It is made up of four chambers:

• Two atria (upper chambers)
• Two ventricles (lower chambers)

The heart also contains valves that regulate blood flow:

• The tricuspid valve connects the right atrium and the right ventricle.
• The mitral valve connects the left atrium and the left ventricle.

Understanding the Cardiac Cycle

The cardiac cycle is the sequence of events that occurs with each heartbeat. As the heart beats, it circulates blood through the body's pulmonary and systemic circuits.

There are two main phases of the cardiac cycle:

• Diastole Phase: The heart ventricles

The structural organization of eukaryotic cells is remarkably complex and compartmentalized, reflecting the diverse functions these cells perform. Eukaryotes encompass a wide array of organisms, including plants, animals, fungi, and protists. Below is a detailed exploration of the structural components of eukaryotic cells:

1. Cell Membrane (Plasma Membrane)

• Composition: The cell's outer boundary is formed by a phospholipid bilayer with embedded proteins and other molecules.
• Function: It regulates the passage of substances into and out of the cell, acting as a selective barrier.

2. Cell Wall (in some cells)

• Present in: Plant cells, fungal cells, and some protists.
• Composition: A rigid structure made of cellulose in plants and chitin in fungi.
• Function:

Understanding Kidney Function

As capillaries exit organs, they converge into larger blood vessels, veins, which eventually return the blood to the heart at the right atrium.

Abnormal Kidney Function:

An individual's kidneys are unable to remove waste, the medical treatment known as hemodialysis. Use a dialysis machine 'artificial kidney' is only temporary, until the patient recovers normal kidney function or receives a kidney transplant. Blood is put in close contact with a special solution similar to blood plasma. The semipermeable membrane allows urea and other waste materials to exit the blood and prevents the escape of blood cells.

Painful Stones:

The substances transported in the urine can trigger the formation of crystals, commonly referred... Continue reading "Understanding Kidney Function, Stones, and Blood Disorders" »

The Central Dogma of Molecular Biology

Replication - General Characteristics:

• DNA replication is semiconservative: each strand in the DNA double helix acts as a template for the synthesis of a new, complementary strand. The new two daughter molecules of DNA have a new strand and an old one.
• DNA polymerase III: is the enzyme that adds nucleotides to the growing DNA chain, incorporating only those that are complementary to the template. DNA polymerase III has the following characteristics:
  • It can only read a template in 3’-----5’ direction so the new strand grows in 5’----3’ direction.
  • It needs a pre-existing strand of nucleotides called a primer which provides a 3’-OH end to bind new nucleotides.
  • It is able to repair the mistakes by removing

Natural Selection: Principles of Adaptation

Natural selection is the principle that variations in the biology or behavior of a species result in some individuals possessing traits that confer an advantage in survival. This process is highly dependent on the environment.

Individuals with these advantageous traits are more likely to survive, prosper, and reproduce. Over time, the population becomes dominated by individuals exhibiting these beneficial biological or behavioral characteristics. Offspring of the same species can be born with mutations, introducing new variations. Natural selection drives populations to become adapted, or increasingly well-suited, to their environments over time. This process relies on the environment and requires existing... Continue reading "Understanding Natural Selection and Brain Functions" »

Arthritis: Inflammation of the Joints

Arthritis is a condition where the joints become inflamed, swollen, and warm to the touch. It can also cause decreased mobility and joint deformities.

Osteoarthritis: A Common Type of Arthritis

Osteoarthritis is a chronic, non-inflammatory condition characterized by progressive degeneration of the cartilage and joints.

Gout: Painful Inflammation of Joints

Gout is a type of arthritis that involves painful inflammation of the joints. It usually begins abruptly and is accompanied by redness and swelling.

Rheumatism: Similar to Osteoarthritis

Rheumatism is similar to osteoarthritis but typically occurs in individuals between the ages of 25 and 55.

Osteoporosis: Decrease in Bone Mass

Osteoporosis is a condition characterized... Continue reading "Common Types of Arthritis and Other Joint Conditions" »

Enzymes: Proteins that Function as Biological Catalysts

1) Singer and Nicolson's fluid mosaic model of the membrane proposed that membranes consist of protein molecules embedded in a fluid bilayer of phospholipids

2) Which component is a peripheral protein?

D

3) Which component is cholesterol?

D

4) Which component is a protein fiber of the extracellular matrix?

A

5) Which component is a microfilament (actin filament) of the cytoskeleton?

C

6) Which component is a glycolipid?

B

7) Which of the following most accurately describes selective permeability?

Only certain molecules can cross a cell membrane.

8) Which of the following would likely move through the lipid bilayer of a plasma membrane most rapidly?

CO2

9) Which of the following allows water to move much faster across cell membranes?

aquaporins

10) Diffusion... Continue reading "Understanding Cell Membrane Components and Functions" »