Neurological Examination: History, Mental Status, Cranial Nerves and Motor Function

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Neurological Examination Summary

History of the Disease (HDA)

  • Inquire about: convulsions, loss of consciousness, headache, vertigo, vision loss, difficulty hearing, tinnitus, swallowing, weakness, difficulty moving, abnormal movements, numbness and tingling, tremor, trouble walking and balance, control of sphincters and sexual activity, memory, thinking, sleep, and depressive symptoms.

Brief Examination

  • Mental state, eye movements, pupils, visual fields, facial movements and speech, strength in the upper and lower limbs, reflexes, painful and touch sensitivity of the hands and feet, static and dynamic balance.

Mental Status

  • Level of consciousness: alertness, drowsiness, coma.
  • Orientation: to time, place, name, date, etc.
  • Attention and concentration: repeats numbers, spells words.
  • Memory: immediate (repeats digits), recent (recalls words previously spoken by the examiner), remote.
  • Language and speech: fluency, coherence, reading, written comprehension, repetition (ask for sequential numbers, increasing until error).
  • Gnosis and praxis: distinguishing right and left, identifying objects by touch, imitating movements.
  • Mini-Mental State Examination

Gait and Balance

  • Gait types
  • Romberg test

Inspection

Palpation and Auscultation

  • Carotid arteries
  • Heart
  • Pulses
  • Orbits

Cranial Nerves

  • I (Olfactory): test each nostril separately.
  • II (Optic): visual fields, fundoscopy, and visual acuity.
  • III, IV and VI (Oculomotor, Trochlear, Abducens): eye movements and pupils (direct, indirect and convergence reflexes), palpebral fissure.
  • V (Trigeminal): sensation of the ophthalmic, maxillary and mandibular branches. Motor: masseter, pterygoid and temporal muscles (ask the patient to open the mouth). Corneal reflex.
  • VII (Facial): eyelid closure, whistling and smiling, forehead wrinkling, trapezius and platysma. Taste on the anterior tongue, tear production.
  • VIII (Vestibulocochlear): cochlear function: whisper test, Rinne and Weber tests. Vestibular function: caloric nystagmus or Romberg test.
  • IX and X (Glossopharyngeal and Vagus): palate and uvula symmetry, palatal reflex, cough, then swallowing, phonation, taste as above.
  • XI (Accessory): strength of the trapezius and sternocleidomastoid.
  • XII (Hypoglossal): tongue volume, symmetry and mobility.

Motor Function

  • Involuntary movements
  • Strength: flexion and extension, abduction and adduction. Graded from 0 to 5. Maneuvers: outstretched arms (pronator drift, Barré). Simulation tests (Hoover, Souque and Hait).
  • Tone: passive resistance of the limb during mobilization while the patient is relaxed. Spasticity (upper motor neuron lesion), rigidity (extrapyramidal), paratonia (frontal lobe lesions and thalamus).
  • Coordination: finger-to-nose test, diadochokinesis and rebound test. Heel-to-knee test. Sitting without support.
  • Reflexes: response speed, amplitude and relaxation. Grading: 0 = absent, 1+ hypoactive, 2+ normal, 3+ brisk, 4+ hyperactive with clonus, 5+ hyperactive with sustained clonus. Symmetry. Tested reflexes: masseter, triceps, biceps, quadriceps, Achilles, Hoffmann sign and clonus (e.g., patellar and ankle). Babinski sign and equivalents.

Sensation

  • Close the eyes and test contralateral areas.
  • Superficial (touch, pain and temperature): shoulders C4, forearm C6, T1; anterior thigh L2; calf L4; toe S1.
  • Deep (proprioception): tuning fork on bony extremities.
  • Position sense: up and down (great toe, limbs).
  • Cortical sensation: two-point discrimination, stereognosis, graphesthesia, cutaneous graphesthesia.
  • Meningeal signs: Kernig, Brudzinski and straight leg raise (SLR).

Neurovegetative Functions

  • Frontal lobe syndromes:
    • 1 (unilateral): contralateral spastic hemiparesis, loss of motivation, mildly elevated mood with disinhibition, primitive reflexes.
    • 2 (left hemisphere lesion): right spastic hemiparesis, motor aphasia, agraphia, bilateral limb apraxia.
    • 3 (right hemisphere lesion): left spastic hemiparesis, left limb apraxia.
    • 4 (bilateral lesion): spastic paraparesis or tetraparesis, pseudobulbar palsy, urinary dysfunction, apathy, akinetic mutism, perseveration, irritable behavior.
  • Parietal lobe syndromes: frequent alterations of language and calculation characteristics of the dominant hemisphere (angular gyrus).

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