mRNA Translation: From Transcription to Protein Synthesis
Transcription and mRNA Processing
Transcription occurs within the nucleus. During this process, introns are removed from the pre-mRNA, creating a mature mRNA molecule. This mature mRNA then migrates from the nucleus to the cytoplasm.
Translation Initiation and Elongation
Once in the cytoplasm, the mRNA is recognized by the ribosome. This recognition occurs via specific sequences in bacteria and the 5' cap in eukaryotes. The ribosome then initiates the translation process.
tRNA molecules act as adapters between amino acids and mRNA. Each tRNA has a region that binds to a specific amino acid and another region, the anticodon, that recognizes a triplet of nucleotides (a codon) in the mRNA.
Translation begins when the ribosome identifies the start...