Protein Properties, Denaturation and Biological Importance
Protein Properties
1. Solubility
Proteins are soluble or insoluble depending on their conformation. When a protein adopts a globular conformation, the radicals (R groups) of the amino acids are oriented outward. The ionized R groups establish weak bonds (hydrogen bridges) with the water molecules. When a protein solubilizes, a shell of water molecules surrounds it, and this first layer of water molecules can prevent other proteins from approaching, which leads to its insolubilization. This property is the basis of the possible hydration of proteins in the buffer systems of living organisms.
2. Amphoteric Capacity
Proteins are amphoteric: they have a complex ionization and can neutralize the variations in pH. They can behave as an acid or as a base,...