Notes, summaries, assignments, exams, and exercises for Biology for Baccalaureate

Airlift Reactor

• Design & Mixing Mechanism: The vessel is split internally into two distinct zones: a riser and a downcomer. Gas is injected exclusively into the bottom of the riser channel. This gas injection lowers the fluid density in the riser compared to the ungassed downcomer. The heavier fluid in the downcomer sinks to the bottom, pushing the lighter, aerated fluid up through the riser and creating a continuous loop.
• Key Advantages: Low shear stress environment (excellent for fragile cell types), no moving mechanical parts to break or leak, energy-efficient, and simple to keep sterile.
• Limitations: Not suitable for high-viscosity fermentation broths. It requires high initial capital investment for custom engineering designs.

Bubble Column

Basement Membrane Structure & Function

Covering & Lining Epithelia

Cell Membrane Transport and Internal Systems

Roles of Membrane Proteins

Membrane proteins perform vital functions necessary for cell survival, communication, and structural integrity.

Adhesion Proteins

• Embedded in the membrane, primarily located on either the outer or inner cell surface.
• They anchor the cell in position within the extracellular matrix or anchor structures inside the cell.

Communication Proteins (Gap Junctions)

• Span the entire membrane.
• Connect to gap junctions in a neighboring cell.
• Form large channels between cells, connecting their cytoplasm.
• Facilitate chemical and electrical signaling between adjacent cells.

Receptor Proteins

• Embedded in the membrane, with the receptor site exposed on one side.
• Signal molecules (i.e., hormones) bind

Zika is a mosquito-borne disease transmitted by the same mosquito that carries the dengue virus. There have also been cases of transmission through sexual intercourse.

Transmission

Most people get Zika from a mosquito bite. Mosquitoes become infected when they feed on the blood of a person already infected with the virus, and when they bite others, they can transmit the virus. Other forms of transmission include:

• A pregnant woman can pass the Zika virus to her fetus during pregnancy or at the time of birth.
• Zika can also be transmitted through sexual intercourse and blood transfusion.

Symptoms

Zika can cause incomplete brain development in fetuses. Common symptoms include fever, rash, joint pain, and conjunctivitis.

Prevention

To reduce the risk of

• Many carbon-based molecules are made of many small subunits bonded together.
• Monomers are the individual subunits.
• Polymers are made of many monomers.
• Four main types of carbon-based molecules are found in living things.
• Carbohydrates are made of carbon, hydrogen, and oxygen. Include sugars and starches. Carbohydrates can be broken down to provide energy for cells. Some carbohydrates are part of cell structure.
• Monosaccharides are simple sugars.
• Polysaccharides include starches, cellulose, and glycogen.
• Polymer (starch)
• Starch is a polymer of glucose monomers that often has a branched structure.
• Polymer (cellulose)
• Cellulose is a polymer of glucose monomers that has a straight, rigid structure
• Many contain carbon chains called fatty acids.
• Fats and oils

T-Cell Coreceptor Specificity

• Helper T-cells require antigen and Class II markers.
• Co-presentation requirements stem from different coreceptors on Killer and Helper T cells:
  • Killer T-cell coreceptor CD8 interacts only with Class I markers.
  • Helper T-cell coreceptor CD4 interacts only with Class II markers.

Interactions: Antigen-Presenting Cells & Lymphocytes

Active Immunity

Primary and Secondary Immune Responses

1. On first exposure to a pathogen, there is a latency of 5-10 days before specific antibodies are made, known as the primary response.
   • Antibody levels plateau after a few days and decline after a few weeks.
2. Subsequent exposure to the same antigen causes a secondary response.
   • Antibody production is much more rapid and sustained.

Clonal Selection

Immunity Fundamentals

The ability to ward off disease through the body's defenses is called immunity.

Understanding Immunity Concepts

• Susceptibility

  Lack of resistance to a disease.

• Immunity Defined

  The ability to ward off disease.

• Genetic Resistance

  The inability of a pathogen to cause disease.

  • Genetic variation in an individual results in a lack of receptors for pathogen binding or other structures required by the pathogen.

• Innate Immunity

  Defenses against any pathogen.

  • Present at birth.
  • Comprises all body defenses that protect the body against any kind of pathogen.

• Adaptive Immunity

  Immunity or resistance to a specific pathogen.

  • Defenses (antibodies) against specific microorganisms.

Innate Immunity Activation

Innate immunity is activated by protein receptors...

Polygenic Inheritance vs. Monogenic Inheritance

Polygenic inheritance refers to the kind of inheritance in which a trait is produced from the cumulative effects of many genes. This is in contrast to monogenic inheritance, wherein a trait results from the expression of one gene (or one gene pair). In humans, height, weight, and skin color are examples of polygenic inheritance, which does not follow a Mendelian pattern of inheritance.

Linkage Groups, Sex Chromosomes, and Autosomal Chromosomes

• Linkage group: A pair or set of genes on a chromosome that tend to be inherited together.
• Sex chromosomes are the ones that determine your gender. These are X and Y (XX in females, XY in males).
• Autosomal chromosomes are the remaining chromosomes that are not

The Heart: Structure and Function

The heart is a contractile, muscular organ, roughly the size of a fist and conical in shape. Its primary function is to pump blood to reach all parts of the body. The heart is situated above the diaphragm, nestled between the lungs.

The heart is composed of two distinct halves, separated by a septum, which ensures the right and left halves do not communicate directly. Each half of the heart has two cavities:

• An upper, thinner-walled cavity called an atrium.
• A lower, muscular-walled cavity called a ventricle, which drives the blood.

Understanding the Cardiac Cycle

The period between the end of one contraction and the end of the subsequent one is called the cardiac cycle. It includes two main phases:

• Diastole: An expansion

Activation Energy and the Activated Complex

Chemical reactions involve the breaking of some bonds in the reactants and the formation of new ones, resulting in specific products. For this to happen, a certain amount of energy, *q*, is required to activate the reactants. This energy is called activation energy and is necessary to initiate the reaction.

Molecules reach a higher-energy activated state or transition state where the bonds are partially broken. Because this reaction takes place, the products obtained are in a lower energy state. The higher the activation energy, the more difficult it will be to reach the activated state, and the reaction rate will be lower. One way to initiate the reaction is by heating the substance; the molecules...